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. 2021 Dec 2;12:780594. doi: 10.3389/fimmu.2021.780594

Table 3.

Effects of covariates on antibody titers after the first and the second dose of mRNA-1273 SARS-CoV-2 vaccine (univariate analysis).

After 1st dose After 2nd dose
β-coefficient t value p value β-coefficient t value p value
Titer after 1st dose NA NA NA 0.44 4.97 1.53 x 10-5
Age -0.05 -1.37 0.18 -0.03 -1.72 0.09
Gender -1.48 -1.92 0.06 -0.80 -1.54 0.13
IS 0.74 0.57 0.57 -0.36 -0.39 0.70
Sodium 0.17 1.43 0.16 0.09 1.61 0.11
Albumin 0.12 1.92 0.36 0.09 1.16 0.25
CRP -0.64 -0.92 0.36 -0.29 -0.62 0.53
Dialysis vintage -0.04 -2.5 0.017 -0.02 -1.07 0.29
BMI 0.04 0.33 0.74 -0.05 -0.83 0.41
Weely total Kt/V 1.49 1.39 0.17 0.76 1.43 0.16
GFR* 0.23 1.78 0.08 0.08 1.30 0.20
Davies Score -0.68 -2.12 0.04 -0.33 -2.01 0.051

Univariate analysis of the variables associated with antibody titers after the first and the second dose of mRNA-1273 vaccine using univariate quantile regression. P<0.05 was considered significant (significant associations marked in bold). IS, immunosuppression; BMI, body mass index; weekly Kt/V, clearance of urea x time/volume; *GFR, residual glomerular filtration rate (calculated as mean of renal creatinine and renal urea clearance using 24 h urine samples).