Skip to main content
. 2021 Dec 2;8:795421. doi: 10.3389/fmed.2021.795421

Table 2.

Prevalence of NAFLD stages among male and female.

Male Female
Overall No/mild (<260) Moderate (260–290) Severe (>290) p-value Overall No/mild (<260) Moderate (260–290) Severe (>290) p-value
Overall 1,596 (48.2%) 745 (47.5%) 254 (16.0%) 597 (36.5%) 1,696 (51.8%) 923 (56.4%) 285 (16.2%) 488 (27.4%)
Race/ethnicity <0.0001 0.059
Mexican American 212 (8.8) 62 (28.3) 39 (17.6) 111 (54.1) 229 (8.1) 95 (45.5) 36 (16.8) 98 (37.7)
Other Hispanic 140 (6.2) 66 (56.3) 23 (14.8) 51 (28.8) 146 (5.9) 81 (56.4) 21 (12.7) 44 (30.9)
Non-Hispanic White 588 (65.7) 259 (47.6) 90 (15.3) 239 (37.1) 632 (65.6) 346 (56.9) 104 (15.7) 182 (27.4)
Non-Hispanic Black 348 (9.5) 208 (60.7) 50 (15.3) 90 (24.0) 370 (10.3) 216 (61.6) 65 (16.7) 89 (21.6)
Other race 308 (9.8) 150 (45.6) 52 (21.1) 106 (33.3) 319 (10.1) 185 (57.0) 59 (20.2) 75 (22.9)
Age (years) <0.0001 <0.0001
18–19 80 (3.3) 59 (81.1) 5 (5.8) 16 (13.1) 85 (3.2) 71 (86.3) 5 (5.1) 9 (8.5)
20–34 356 (29.7) 206 (60.3) 47 (10.9) 103 (28.7) 386 (25.1) 273 (71.8) 50 (12.1) 63 (16.1)
35–49 334 (23.7) 146 (47.3) 52 (15.9) 136 (36.8) 394 (23.6) 206 (54.6) 72 (18.8) 116 (26.5)
50–64 447 (26.8) 172 (34.7) 85 (19.9) 190 (45.4) 475 (28.3) 205 (48.7) 88 (17.5) 182 (33.8)
65+ 379 (16.5) 162 (38.5) 65 (21.1) 152 (40.4) 356 (19.8) 168 (45.4) 70 (17.9) 118 (36.8)
Education 0.068 0.039
Less than high school 322 (11.0) 153 (46.3) 54 (21.7) 115 (31.9) 254 (8.8) 133 (55.3) 41 (17.3) 80 (27.5)
High school 406 (29.6) 200 (48.6) 61 (12.7) 145 (38.7) 415 (26.8) 221 (52.6) 59 (15.2) 135 (32.2)
Some college 484 (29.0) 215 (45.7) 70 (12.8) 199 (41.5) 613 (32.5) 321 (52.0) 110 (17.0) 182 (30.9)
At least college degree 384 (30.3) 177 (48.5) 69 (20.4) 138 (31.2) 414 (31.9) 248 (64.6) 75 (15.7) 91 (19.7)
Language spoken at home 0.522 0.182
English 1,141 (82.2) 556 (48.2) 176 (16.4) 409 (35.4) 1,217 (83.6) 688 (57.8) 200 (15.7) 329 (26.5)
Spanish 106 (3.5) 34 (33.3) 20 (18.0) 52 (48.6) 113 (3.5) 49 (44.7) 20 (16.8) 44 (38.5)
Both 173 (7.7) 70 (45.2) 26 (12.2) 77 (42.6) 184 (7.1) 85 (49.8) 27 (16.2) 72 (34.0)
Other 176 (6.6) 85 (48.4) 32 (15.4) 59 (36.2) 182 (5.9) 101 (52.7) 38 (21.6) 43 (25.7)
Federal income ratio (FIR) 0.108 0.648
<1 281 (10.6) 157 (58.8) 29 (10.2) 95 (31.0) 335 (14.1) 188 (56.5) 51 (15.2) 96 (28.3)
1–2 430 (18.4) 190 (47.2) 70 (16.1) 170 (36.7) 460 (20.7) 245 (55.5) 85 (19.5) 130 (25.0)
>2 885 (71.1) 398 (45.9) 155 (16.9) 332 (37.2) 901 (65.2) 490 (56.7) 149 (15.3) 262 (28.0)
Waist-hip ratio <0.0001 <0.0001
Healthy 990 (64.6) 593 (62.2) 160 (14.7) 237 (23.1) 452 (29.4) 373 (86.7) 43 (6.8) 36 (6.5)
Risk for women (≥0.85%)/risk for men (≥1.0%) 606 (35.4) 152 (20.6) 94 (18.4) 360 (61.0) 1,244 (70.6) 550 (43.8) 242 (20.0) 452 (36.1)
BMI <0.0001 <0.0001
Normal or healthy (<25) 416 (23.5) 350 (87.8) 35 (6.2) 31 (6.0) 518 (32.2) 443 (89.4) 48 (7.4) 27 (3.2)
Overweight (25– <30) 586 (35.2) 280 (50.8) 130 (23.8) 176 (25.4) 465 (27.0) 264 (57.9) 78 (17.0) 123 (25.1)
Obese (≥30) 594 (41.3) 115 (21.6) 89 (15.0) 390 (63.3) 713 (40.8) 216 (29.5) 159 (22.5) 338 (48.1)
Smoking status 0.001 0.001
Current 317 (17.1) 203 (64.9) 33 (11.7) 81 (23.4) 233 (14.2) 130 (54.8) 37 (18.6) 66 (26.5)
Former 466 (31.1) 168 (38.4) 89 (19.3) 209 (42.3) 292 (18.0) 134 (46.7) 48 (18.0) 110 (35.4)
Non-smoker 813 (51.7) 374 (47.2) 132 (15.5) 307 (37.3) 1,171 (67.8) 659 (59.4) 200 (15.1) 312 (25.5)
Physical activity 0.024 <0.0001
Inactive 294 (14.3) 113 (36.7) 45 (15.3) 136 (48.0) 439 (22.5) 205 (48.2) 88 (19.0) 146 (32.9)
Does not meet guideline 205 (12.6) 88 (38.1) 28 (17.2) 89 (44.7) 310 (17.7) 153 (46.6) 49 (12.8) 108 (40.6)
Meets guidelines 1,097 (73.1) 544 (51.2) 181 (16.0) 372 (32.8) 947 (59.8) 565 (62.5) 148 (16.1) 234 (21.4)
Healthy eating index 0.537 <0.0001
Poor diet 1,154 (72.9) 542 (46.9) 179 (15.5) 433 (37.6) 1,150 (70.0) 615 (52.5) 200 (18.0) 335 (29.4)
Needs improvement 404 (25.0) 185 (47.7) 68 (18.3) 151 (34.0) 483 (26.8) 275 (64.7) 72 (11.7) 136 (23.6)
Good diet 38 (2.0) 18 (64.7) 7 (8.6) 13 (26.7) 63 (3.1) 33 (73.2) 13 (12.2) 17 (14.5)
Serum cholesterol 0.006 0.125
Good (<200 mg/dL) 1,075 (65.9) 527 (50.8) 167 (16.5) 381 (32.8) 1,062 (59.7) 616 (59.7) 163 (14.9) 283 (25.4)
Elevated (200–239 mg/dL) 374 (24.6) 163 (43.8) 64 (16.1) 147 (40.1) 451 (29.4) 221 (50.7) 83 (16.7) 147 (32.6)
High (≥240 mg/dL) 147 (9.5) 55 (34.1) 23 (12.7) 69 (53.2) 183 (10.9) 86 (53.7) 39 (21.7) 58 (24.6)
High-density lipoproteins <0.0001 <0.0001
Low (<40 mg/dL) 410 (23.9) 118 (30.5) 69 (15.4) 223 (54.1) 146 (7.6) 39 (22.2) 22 (15.1) 85 (62.7)
Borderline risk (40–59 mg/dL) 920 (60.7) 444 (47.9) 147 (16.9) 329 (35.1) 865 (48.8) 409 (48.7) 154 (16.9) 302 (34.4)
Healthy (≥60 mg/dL) 266 (15.5) 183 (71.9) 38 (13.6) 45 (14.6) 685 (43.6) 475 (71.0) 109 (15.5) 101 (13.5)
Serum triglycerides <0.0001 <0.0001
Normal (<150 mg/dL) 990 (61.0) 575 (60.0) 143 (15.0) 272 (24.9) 1,246 (73.5) 795 (66.3) 196 (14.8) 255 (18.9)
Borderline (150–199 mg/dL) 255 (16.3) 89 (33.5) 56 (21.3) 110 (45.2) 250 (15.4) 76 (34.8) 57 (24.0) 117 (41.3)
High (≥200 mg/dL) 351 (22.6) 81 (23.7) 55 (14.9) 215 (61.4) 200 (11.1) 52 (21.2) 32 (14.1) 116 (64.7)
High-sensitivity CRP <0.0001 <0.0001
Normal (0.1– <1 mg/dL) 522 (33.1) 331 (65.8) 72 (13.1) 119 (21.1) 482 (29.4) 374 (78.4) 65 (11.8) 43 (9.9)
Mild inflammation (1– <3 mg/dL) 635 (40.8) 265 (42.2) 115 (19.7) 255 (38.0) 536 (31.8) 294 (57.4) 102 (19.6) 140 (23.0)
Significant inflammation (3– <10 mg/dL) 370 (21.9) 125 (33.1) 52 (14.4) 193 (52.5) 514 (29.6) 203 (40.9) 92 (16.4) 219 (42.8)
High significant inflammation (≥10 mg/dL) 69 (4.2) 24 (29.1) 15 (11.4) 30 (59.4) 164 (9.1) 52 (33.1) 26 (17.5) 86 (49.4)
Aspartate aminotransferase (AST) 0.452 0.012
Normal (≤ 40 U/L) 1,518 (94.3) 714 (47.9) 247 (16.3) 557 (35.8) 1,647 (97.7) 903 (56.9) 277 (16.2) 467 (26.9)
Elevated (>40 U/L) 78 (5.7) 31 (40.4) 7 (11.6) 40 (48.0) 49 (2.3) 20 (37.0) 8 (14.8) 21 (48.2)
Alanine aminotransferase (ALT) 0.062 0.022
Normal (≤ 56 U/L) 1,513 (94.3) 722 (48.5) 244 (16.2) 547 (35.4) 1,666 (98.4) 912 (56.7) 282 (16.3) 472 (27.0)
Elevated (>56 U/L) 83 (5.7) 23 (31.1) 10 (13.9) 50 (55.0) 30 (1.6) 11 (40.1) 3 (10.2) 16 (49.8)
Hemoglobin A1c (HbA1c%) <0.0001 <0.0001
Healthy (<5.7%) 876 (66.5) 499 (57.7) 126 (15.6) 251 (26.7) 1,026 (67.9) 695 (66.9) 161 (16.0) 170 (17.1)
Pre-diabetes (5.7–6.4%) 489 (23.7) 187 (31.5) 97 (18.4) 205 (50.1) 464 (23.8) 191 (41.0) 88 (17.7) 185 (41.3)
Diabetes (≥6.5%) 231 (9.9) 59 (17.2) 31 (13.3) 141 (69.5) 206 (8.3) 37 (15.2) 36 (12.9) 133 (71.9)