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. 2021 Dec 2;8:795421. doi: 10.3389/fmed.2021.795421

Table 4.

Adjusted odds ratio (OR) and 95% confidence interval (CI) for the relationship between NAFLD and race/ethnicity (reference = no/mild NAFLD).

Reference = no/mild NAFLD Moderate (260–290) Severe (>290)
AOR [95% CI] p-value AOR [95% CI] p-value
Race/Ethnicity
Mexican-American vs. non-Hispanic White 1.9 [1.1–3.4] 0.0178 2.4 [1.4–4.2] 0.0015
Other Hispanic vs. non-Hispanic White 0.9 [0.5–1.4] 0.5159 0.7 [0.4–1.2] 0.1807
Non-Hispanic Black vs. non-Hispanic White 0.9 [0.6–1.3] 0.5245 0.5 [0.4–0.7] <0.0001
Other race vs. non-Hispanic White 1.7 [0.9–3.1] 0.1010 1.0 [0.6–1.8] 0.9419
Age (years)
18–19 vs. 20–34 0.6 [0.3–1.3] 0.1904 0.6 [0.3–1.2] 0.1671
35–49 vs. 20–34 1.4 [1.0–2.1] 0.0723 1.2 [0.8–1.7] 0.3900
50–64 vs. 20–34 2.3 [1.3–4.3] 0.0059 2.1 [1.4–3.1] 0.0007
65+ vs. 20–34 2.0 [1.1–3.7] 0.0346 1.6 [0.9–2.7] 0.0932
Education
Less than high school vs. high school 1.4 [1.0–2.0] 0.0373 0.7 [0.4–1.2] 0.2138
Some college vs. high school 1.2 [0.7–2.0] 0.5723 1.1 [0.7–1.9] 0.6944
At least college degree vs. high school 1.4 [0.8–2.7] 0.2785 0.9 [0.5–1.6] 0.7864
Language spoken at home
Spanish vs. English 0.8 [0.5–1.4] 0.4419 0.8 [0.5–1.4] 0.4560
Both vs. English 0.8 [0.5–1.4] 0.4874 1.1 [0.6–2.0] 0.8350
Other vs. English 1.2 [0.6–2.5] 0.5989 1.5 [0.8–3.0] 0.2312
Federal income ratio (FIR)
<1 vs. >2 0.8 [0.6–1.1] 0.2188 0.8 [0.6–1.2] 0.2640
1–2 vs. >2 1.1 [0.7–1.8] 0.6418 0.9 [0.6–1.2] 0.3799
Waist-hip ratio
Risk for women (≥0.85)/risk for men (≥1.0) vs. healthy 1.7 [1.1–2.8] 0.0249 1.8 [1.2–2.7] 0.0041
BMI
Overweight (25– <30) vs. normal (<25) 3.9 [2.4–6.6] <0.0001 7.1 [3.9–13.1] <0.0001
Obese (≥30) vs. normal (<25) 6.5 [3.7–11.6] <0.0001 24.8 [11.9–51.9] <0.0001
Smoking status
Current vs. never 0.9 [0.6–1.4] 0.5794 0.7 [0.5–1.1] 0.1166
Former vs. never 1.2 [0.9–1.6] 0.3316 1.2 [0.9–1.7] 0.2279
Alcohol use
Current vs. never 1.4 [0.9–2.3] 0.1269 0.7 [0.4–1.2] 0.1888
Former vs. never 1.4 [0.9–2.3] 0.1717 0.6 [0.3–1.1] 0.1136
Physical activity
Inactive vs. meets guidelines 1.0 [0.8–1.4] 0.8087 1.2 [0.9–1.8] 0.2674
Does not meet guidelines vs. meets guidelines 0.9 [0.5–1.6] 0.6670 1.4 [0.9–2.2] 0.1557
Healthy eating index
Poor diet vs. good diet 1.6 [0.7–3.9] 0.2610 0.9 [0.2–3.9] 0.9219
Needs improvement vs. good diet 1.2 [0.5–3.3] 0.6525 0.9 [0.2–3.4] 0.8771
Serum cholesterol
Elevated (200–239 mg/dL) vs. good (<200 mg/dL) 0.8 [0.5–1.2] 0.2176 0.9 [0.7–1.3] 0.7105
High (≥240 mg/dL) vs. good (<200 mg/dL) 0.8 [0.6–1.1] 0.1756 0.8 [0.6–1.1] 0.1753
High-density lipoproteins
Low (<40 mg/dL) vs. healthy (≥60 mg/dL) 1.2 [0.6–2.7] 0.5843 2.7 [1.6–4.7] 0.0003
Borderline risk (40–59 mg/dL) vs. healthy (≥60 mg/dL) 1.2 [0.8–1.7] 0.4582 1.8 [1.2–2.6] 0.0032
Serum triglycerides
Borderline (150–199 mg/dL) vs. normal (<150 mg/dL) 1.8 [1.3–2.4] 0.0009 1.7 [1.0–2.8] 0.0375
High (≥200 mg/dL) vs. normal (<150 mg/dL) 1.7 [1.3–2.4] 0.0007 2.9 [1.9–4.4] <0.0001
High-sensitivity CRP
Mild inflammation (1–3 mg/dL) vs. normal (<1 mg/dL) 1.4 [0.9–2.2] 0.1638 1.2 [0.7–2.0] 0.4566
Significant inflammation (3–10 mg/dL) vs. normal (<1 mg/dL) 1.1 [0.7–1.7] 0.7856 1.4 [0.8–2.5] 0.2684
High significant inflammation (≥10 mg/dL) 1.3 [0.8–2.0] 0.2317 1.8 [0.8–4.0] 0.1597
Aspartate aminotransferase (AST)
Elevated (>40 U/L) vs. normal (≤ 40 U/L) 1.4 [0.3–6.3] 0.6815 1.9 [0.7–5.0] 0.2018
Alanine aminotransferase (ALT)
Elevated (>56 U/L) vs. normal (≤ 56 U/L) 1.3 [0.3–4.6] 0.7310 1.9 [0.6–6.2] 0.2611
Hemoglobin A1c (HbA1c)
Pre-diabetes vs. healthy (<5.7%) 1.3 [0.9–1.9] 0.2221 2.4 [1.7–3.6] <0.0001
Diabetes (≥6.5%) vs. healthy (<5.7%) 1.6 [0.9–2.8] 0.1469 5.0 [2.6–9.3] <0.0001

Bold = statistically significant at p < 0.05.