Table 4.
Reference = no/mild NAFLD | Moderate (260–290) | Severe (>290) | ||
---|---|---|---|---|
AOR [95% CI] | p-value | AOR [95% CI] | p-value | |
Race/Ethnicity | ||||
Mexican-American vs. non-Hispanic White | 1.9 [1.1–3.4] | 0.0178 | 2.4 [1.4–4.2] | 0.0015 |
Other Hispanic vs. non-Hispanic White | 0.9 [0.5–1.4] | 0.5159 | 0.7 [0.4–1.2] | 0.1807 |
Non-Hispanic Black vs. non-Hispanic White | 0.9 [0.6–1.3] | 0.5245 | 0.5 [0.4–0.7] | <0.0001 |
Other race vs. non-Hispanic White | 1.7 [0.9–3.1] | 0.1010 | 1.0 [0.6–1.8] | 0.9419 |
Age (years) | ||||
18–19 vs. 20–34 | 0.6 [0.3–1.3] | 0.1904 | 0.6 [0.3–1.2] | 0.1671 |
35–49 vs. 20–34 | 1.4 [1.0–2.1] | 0.0723 | 1.2 [0.8–1.7] | 0.3900 |
50–64 vs. 20–34 | 2.3 [1.3–4.3] | 0.0059 | 2.1 [1.4–3.1] | 0.0007 |
65+ vs. 20–34 | 2.0 [1.1–3.7] | 0.0346 | 1.6 [0.9–2.7] | 0.0932 |
Education | ||||
Less than high school vs. high school | 1.4 [1.0–2.0] | 0.0373 | 0.7 [0.4–1.2] | 0.2138 |
Some college vs. high school | 1.2 [0.7–2.0] | 0.5723 | 1.1 [0.7–1.9] | 0.6944 |
At least college degree vs. high school | 1.4 [0.8–2.7] | 0.2785 | 0.9 [0.5–1.6] | 0.7864 |
Language spoken at home | ||||
Spanish vs. English | 0.8 [0.5–1.4] | 0.4419 | 0.8 [0.5–1.4] | 0.4560 |
Both vs. English | 0.8 [0.5–1.4] | 0.4874 | 1.1 [0.6–2.0] | 0.8350 |
Other vs. English | 1.2 [0.6–2.5] | 0.5989 | 1.5 [0.8–3.0] | 0.2312 |
Federal income ratio (FIR) | ||||
<1 vs. >2 | 0.8 [0.6–1.1] | 0.2188 | 0.8 [0.6–1.2] | 0.2640 |
1–2 vs. >2 | 1.1 [0.7–1.8] | 0.6418 | 0.9 [0.6–1.2] | 0.3799 |
Waist-hip ratio | ||||
Risk for women (≥0.85)/risk for men (≥1.0) vs. healthy | 1.7 [1.1–2.8] | 0.0249 | 1.8 [1.2–2.7] | 0.0041 |
BMI | ||||
Overweight (25– <30) vs. normal (<25) | 3.9 [2.4–6.6] | <0.0001 | 7.1 [3.9–13.1] | <0.0001 |
Obese (≥30) vs. normal (<25) | 6.5 [3.7–11.6] | <0.0001 | 24.8 [11.9–51.9] | <0.0001 |
Smoking status | ||||
Current vs. never | 0.9 [0.6–1.4] | 0.5794 | 0.7 [0.5–1.1] | 0.1166 |
Former vs. never | 1.2 [0.9–1.6] | 0.3316 | 1.2 [0.9–1.7] | 0.2279 |
Alcohol use | ||||
Current vs. never | 1.4 [0.9–2.3] | 0.1269 | 0.7 [0.4–1.2] | 0.1888 |
Former vs. never | 1.4 [0.9–2.3] | 0.1717 | 0.6 [0.3–1.1] | 0.1136 |
Physical activity | ||||
Inactive vs. meets guidelines | 1.0 [0.8–1.4] | 0.8087 | 1.2 [0.9–1.8] | 0.2674 |
Does not meet guidelines vs. meets guidelines | 0.9 [0.5–1.6] | 0.6670 | 1.4 [0.9–2.2] | 0.1557 |
Healthy eating index | ||||
Poor diet vs. good diet | 1.6 [0.7–3.9] | 0.2610 | 0.9 [0.2–3.9] | 0.9219 |
Needs improvement vs. good diet | 1.2 [0.5–3.3] | 0.6525 | 0.9 [0.2–3.4] | 0.8771 |
Serum cholesterol | ||||
Elevated (200–239 mg/dL) vs. good (<200 mg/dL) | 0.8 [0.5–1.2] | 0.2176 | 0.9 [0.7–1.3] | 0.7105 |
High (≥240 mg/dL) vs. good (<200 mg/dL) | 0.8 [0.6–1.1] | 0.1756 | 0.8 [0.6–1.1] | 0.1753 |
High-density lipoproteins | ||||
Low (<40 mg/dL) vs. healthy (≥60 mg/dL) | 1.2 [0.6–2.7] | 0.5843 | 2.7 [1.6–4.7] | 0.0003 |
Borderline risk (40–59 mg/dL) vs. healthy (≥60 mg/dL) | 1.2 [0.8–1.7] | 0.4582 | 1.8 [1.2–2.6] | 0.0032 |
Serum triglycerides | ||||
Borderline (150–199 mg/dL) vs. normal (<150 mg/dL) | 1.8 [1.3–2.4] | 0.0009 | 1.7 [1.0–2.8] | 0.0375 |
High (≥200 mg/dL) vs. normal (<150 mg/dL) | 1.7 [1.3–2.4] | 0.0007 | 2.9 [1.9–4.4] | <0.0001 |
High-sensitivity CRP | ||||
Mild inflammation (1–3 mg/dL) vs. normal (<1 mg/dL) | 1.4 [0.9–2.2] | 0.1638 | 1.2 [0.7–2.0] | 0.4566 |
Significant inflammation (3–10 mg/dL) vs. normal (<1 mg/dL) | 1.1 [0.7–1.7] | 0.7856 | 1.4 [0.8–2.5] | 0.2684 |
High significant inflammation (≥10 mg/dL) | 1.3 [0.8–2.0] | 0.2317 | 1.8 [0.8–4.0] | 0.1597 |
Aspartate aminotransferase (AST) | ||||
Elevated (>40 U/L) vs. normal (≤ 40 U/L) | 1.4 [0.3–6.3] | 0.6815 | 1.9 [0.7–5.0] | 0.2018 |
Alanine aminotransferase (ALT) | ||||
Elevated (>56 U/L) vs. normal (≤ 56 U/L) | 1.3 [0.3–4.6] | 0.7310 | 1.9 [0.6–6.2] | 0.2611 |
Hemoglobin A1c (HbA1c) | ||||
Pre-diabetes vs. healthy (<5.7%) | 1.3 [0.9–1.9] | 0.2221 | 2.4 [1.7–3.6] | <0.0001 |
Diabetes (≥6.5%) vs. healthy (<5.7%) | 1.6 [0.9–2.8] | 0.1469 | 5.0 [2.6–9.3] | <0.0001 |
Bold = statistically significant at p < 0.05.