Table 1. Demographics and clinicopathologic characteristics of patients with CSCLC, NSCLC, and pure SCLC.
Characteristics | CSCLC (n=871) | NSCLC (n=280,391) | P1 value | Pure SCLC (n=45,433) | P2 value | ||||
---|---|---|---|---|---|---|---|---|---|
Number | % | Number | % | Number | % | ||||
Age (years) | 0.066 | 0.298 | |||||||
≤60 | 229 | 26.3 | 71,494 | 25.5 | 12,775 | 28.1 | |||
60–70 | 305 | 35.0 | 89,909 | 32.1 | 16,162 | 35.6 | |||
>70 | 337 | 38.7 | 118,988 | 42.4 | 16,496 | 36.3 | |||
Gender | 0.099 | <0.001 | |||||||
Female | 378 | 43.4 | 129,512 | 46.2 | 22,700 | 50.0 | |||
Male | 493 | 56.6 | 150,879 | 53.8 | 22,733 | 50.0 | |||
Race | <0.001 | 0.003 | |||||||
White | 727 | 83.5 | 224,921 | 80.2 | 39,384 | 86.7 | |||
Black | 109 | 12.5 | 34,226 | 12.2 | 4,157 | 9.1 | |||
Other | 35 | 4.0 | 21,244 | 7.6 | 1,892 | 4.2 | |||
Primary site | <0.001 | <0.001 | |||||||
Left upper lobe | 217 | 24.9 | 66,680 | 23.8 | 9,921 | 21.8 | |||
Left lower lobe | 100 | 11.5 | 33,018 | 11.8 | 4,159 | 9.2 | |||
Right upper lobe | 270 | 31.0 | 86,587 | 30.9 | 11,949 | 26.3 | |||
Right middle lobe | 32 | 3.7 | 12,179 | 4.3 | 1,860 | 4.1 | |||
Right lower lobe | 100 | 11.5 | 42,316 | 15.1 | 4,952 | 10.9 | |||
Main bronchus | 66 | 7.6 | 11,450 | 4.1 | 5,539 | 12.2 | |||
Unspecific | 86 | 9.9 | 28,161 | 10.0 | 7,053 | 15.5 | |||
T | 0.014 | <0.001 | |||||||
T1 | 184 | 21.1 | 61,292 | 21.9 | 5,276 | 11.6 | |||
T2 | 291 | 33.4 | 92,440 | 33.0 | 11,830 | 26.0 | |||
T3 | 36 | 4.1 | 18,775 | 6.7 | 2,098 | 4.6 | |||
T4 | 360 | 41.3 | 107,884 | 38.5 | 26,229 | 57.7 | |||
N | <0.001 | <0.001 | |||||||
N0 | 285 | 32.7 | 119,329 | 42.6 | 7,029 | 15.5 | |||
N1 | 83 | 9.5 | 26,116 | 9.3 | 3,325 | 7.3 | |||
N2 | 375 | 43.1 | 100,578 | 35.9 | 26,110 | 57.5 | |||
N3 | 128 | 14.7 | 34,368 | 12.3 | 8,969 | 19.7 | |||
M | 0.006 | <0.001 | |||||||
M0 | 460 | 52.8 | 161,104 | 57.5 | 17,051 | 37.5 | |||
M1 | 411 | 47.2 | 119,287 | 42.5 | 28,382 | 62.5 | |||
Surgery | 0.537 | <0.001 | |||||||
None | 626 | 71.9 | 198,855 | 70.9 | 44,275 | 97.5 | |||
Yes | 245 | 28.1 | 81,536 | 29.1 | 1,158 | 2.5 | |||
Radiation | 0.009 | 0.196 | |||||||
None | 473 | 54.3 | 164,501 | 58.7 | 23,669 | 52.1 | |||
Yes | 398 | 45.7 | 115,890 | 41.3 | 21,764 | 47.9 | |||
Chemotherapy | <0.001 | <0.001 | |||||||
None | 306 | 35.1 | 152,260 | 54.3 | 12,780 | 28.1 | |||
Yes | 565 | 64.9 | 128,131 | 45.7 | 32,653 | 71.9 |
CSCLC, combined small cell lung cancer; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer.