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. 2021 Dec 11;13:2141–2151. doi: 10.2147/NSS.S337171

Table 3.

Differences in Sleep Time and Blood Biochemical Factors Across Cumulative Dietary Tryptophan Intake

Dietary Tryptophan Intake in Tertiles Dietary Tryptophan Intake in Continuous Form
T1 T2 T3 Effect Size P for Trend Effect Size P-Value
Sleep time (h) 8.10 (0.027) 8.12 (0.025) 8.19 (0.027) 0.042 (0.020) 0.033 0.055(0.016) 0.001
FPG (mmol/L) 5.58 (0.040) 5.38 (0.038) 5.39 (0.042) −0.091 (0.030) 0.003 −0.097 (0.021) <0.001
HbA1c (%) 5.86 (0.026) 5.56 (0.025) 5.56 (0.027) −0.148 (0.020) <0.001 −0.152(0.016) <0.001
TC (mmol/L) 4.98 (0.027) 4.92 (0.026) 4.84 (0.028) −0.072 (0.021) <0.001 −0.063(0.017) <0.001
LDL-C (mmol/L) 3.11 (0.026) 2.99 (0.025) 2.95 (0.028) −0.081 (0.020) <0.001 −0.071(0.016) <0.001
APO-B (g/L) 0.93 (0.007) 0.89 (0.007) 0.88 (0.007) −0.021 (0.005) <0.001 −0.018(0.004) <0.001

Notes: Multivariable generalized linear models were used to probe for differences across tertiles of tryptophan consumption with adjustment for sex, age, BMI, WHR, smoking status, drinking status, living site, physical activity, urban index, cardiovascular disease, AHEI, SFA, fiber, sugar, fruit, vegetable, and energy intake. Multivariable linear regression models were used to calculate the effect sizes per 1 mg/g protein increment of tryptophan, adjusting for the same variables. Data are mean (SD).

Abbreviations: FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; APO-B, apolipoprotein B; BMI, body mass index; WHR, waist-to-hip ratio; AHEI, Alternate Healthy Eating Index; SFA, saturated fatty acid.