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. 2021 Dec 2;12:792691. doi: 10.3389/fimmu.2021.792691

Table 5.

Summary of cancer vaccine and oncolytic virus therapies for colorectal cancer (CRC).

Regimen Target population Design Registration number Reference
AD5 CEA Vaccine CRC
Lung Cancer
Breast Cancer
Phase I, II NCT01147965 (274)
CEA (6D) VRP Vaccine (AVX701) CRC
Lung Cancer
Breast Cancer
Pancreatic Cancer
Colon Cancer
Phase I, II NCT00529984 Completed
CRC stage III Phase I NCT01890213 Completed
DC/PANVAC or GM-CSF CRC
Metastasis Cancers
Phase II NCT00103142 (275)
Modified vaccine Ankara–5T mCRC / ISRCTN54669986 (276)
GVAX Colon Vaccine mCRC Phase II NCT02981524 Completed
MVA-Brachyury-TRICOM CRC Phase I NCT02179515 (277)
Bavarian Nordic (BN)-CV301 CRC Phase I / (278)