Table 2. Results of the Unadjusted Multinomial Logistic Regression Modelsa.
| Variable | DVT only vs none (n = 277) | PE vs none (n = 40) | PT vs none (n = 117) | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Age at admission | 1.02 (1.00-1.04) | .06 | 0.97 (0.92-1.02) | .19 | 1.02 (0.99-1.05) | .16 |
| Sex (female vs male) | 0.78 (0.58-1.04) | .09 | 1.23 (0.62-2.42) | .55 | 0.83 (0.53-1.29) | .40 |
| Head injury | 2.40 (1.88-3.05) | <.001 | 0.82 (0.40-1.67) | .58 | 1.05 (0.70-1.56) | .83 |
| Spinal cord injury | 2.90 (1.95-4.31) | <.001 | 1.94 (0.59-6.32) | .27 | 2.48 (1.32-4.66) | .005 |
| Shock on admission (SBP <90 mm Hg) | 2.71 (1.93-3.82) | <.001 | 5.76 (2.86-11.6) | <.001 | 5.24 (3.42-8.01) | <.001 |
| Chest injury | 1.81 (1.42-2.31) | <.001 | 2.77 (1.48-5.17) | .001 | 2.55 (1.77-3.68) | <.001 |
| Abdominal injury | 1.97 (1.53-2.54) | <.001 | 2.79 (1.49-5.24) | .001 | 2.45 (1.68-3.56) | <.001 |
| Pelvic fracture | 1.55 (1.17-2.05) | .002 | 2.85 (1.50-5.43) | .001 | 1.71 (1.13-2.60) | .01 |
| Long bone fracture | 0.98 (0.76-1.27) | .88 | 1.43 (0.76-2.69) | .27 | 1.39 (0.95-2.02) | .09 |
| Venous injury | 2.62 (1.82-3.77) | <.001 | 5.09 (2.41-10.8) | <.001 | 2.58 (1.48-4.47) | <.001 |
| Femoral venous catheter | 5.88 (4.41-7.84) | <.001 | 7.32 (3.69-14.5) | <.001 | 4.88 (3.12-7.63) | <.001 |
| Major operative procedure (≥1 h) | 1.75 (1.28-2.40) | <.001 | 6.98 (1.68-28.9) | .007 | 2.70 (1.54-4.74) | <.001 |
| ≥4 d of ventilatory support | 6.44 (5.04-8.23) | <.001 | 12.2 (6.36-23.5) | <.001 | 4.11 (2.82-6.01) | <.001 |
| Tranexamic administration | 2.49 (1.80-3.43) | <.001 | 3.96 (1.92-8.13) | <.001 | 1.23 (0.66-2.30) | .52 |
| Coagulopathy (INR >1.5) | 3.89 (2.52-6.02) | <.001 | 5.61 (2.17-14.5) | <.001 | 3.27 (1.63-6.56) | <.001 |
| History of VTE | 0 | .15 | 0 | .58 | 4.45 (1.05-18.9) | .04 |
| Current cancer | 2.25 (0.53-9.56) | .27 | 0 | .61 | 0 | .39 |
| Pregnancy or recently post partum (within last 3 mo) | 0.32 (0.04-2.32) | .26 | 0 | .34 | 0.76 (0.11-5.54) | .79 |
| Hormone therapy | 1.06 (0.47-2.42) | .89 | 2.53 (0.60-10.6) | .20 | 1.26 (0.40-4.02) | .69 |
| Inflammatory bowel disease | 1.17 (0.16-8.69) | .88 | 0 | .62 | 2.78 (0.37-20.8) | .32 |
| Heparin | ||||||
| 5000 U 2 times daily | 2.31 (1.20-4.45) | .01 | 4.99 (1.52-16.4) | .008 | 2.75 (1.10-6.86) | .03 |
| 5000 U 3 times daily | 2.04 (1.54-2.69) | <.001 | 2.05 (1.00-4.20) | .05 | 1.27 (0.78-2.06) | .34 |
| Enoxaparin | ||||||
| 30 mg Twice daily | 0.45 (0.34-0.58) | <.001 | 0.39 (0.19-0.81) | .01 | 0.77 (0.53-1.11) | .16 |
| 40 mg Once daily | 1.30 (0.96-1.76) | .09 | 0.44 (0.13-1.41) | .17 | 0.45 (0.23-0.89) | .02 |
| Prophylaxis | ||||||
| Other | 0.91 (0.28-2.88) | .87 | 0 | .33 | 0.71 (0.10-5.16) | .74 |
| No | 0.82 (0.53-1.28) | .39 | 1.68 (0.70-4.02) | .24 | 1.40 (0.81-2.42) | .23 |
Abbreviations: DVT, deep vein thrombosis; INR, international normalized ratio; OR, odds ratio; PE, pulmonary emboli; PT, pulmonary thrombosis; SBP, systolic blood pressure; VTE, venous thromboembolism.
a
For associations with P < .10, these variables entered the backward elimination selection process for multivariable logistic regression model development. Likelihood ratio test P value is reported if there were 0 events in a variable category.