FIG. 5.

c-myc and EMCV IRES activities in transgenic adult tissues. Different organs (named on the left) were prepared from adult transgenic mice, and luciferase activities were measured as described for Fig. 4. IRES activities are represented by histograms corresponding to the equation 100 × (LucF/LucR) (Table 2). These values correspond to representative experiments that were repeated at least three times on the two independent lines expressing each bicistronic construct, pCRMyL (c-myc) and pCREL (EMCV). Abbreviations: nd, not done; ud, undetectable LucR activity.