Table 5.

Cut-off scores, sensitivities, specificities and AUCs (95% CI) of the MoCA and MMSE between normal cognition, MCI and dementia by different educational levels within each age group.

Variable		Normal	MCI	Dementia	Normal vs. MCI				Normal vs. Dementia
					Sensitivity	Specificity	Cut-off	AUC (95%CI)	Sensitivity	Specificity	Cut-off	AUC (95%CI)
Age ≤ 75 years and		N = 232	N = 114	N = 26
education ≤ 6 years	MMSE	25.75 ± 3.58	23.19 ± 4.68	16.33 ± 7.23	75.00	52.17	26.5	0.67 (0.61:0.73)	87.50	78.26	23.5	0.90 (0.85:0.96)
	MoCA	20.98 ± 5.10	16.91 ± 4.68	10.62 ± 5.73	72.48	68.53	19.5	0.74 (0.68:0.79)**	92.31	76.29	18.5	0.91 (0.87:0.96)
Age > 75 years and		N = 191	N = 184	N = 113
education ≤ 6 years	MMSE	23.33 ± 4.53	18.83 ± 4.45	11.95 ± 6.68	81.14	61.90	22.5	0.77 (0.72:0.82)*	84.68	83.60	19.5	0.92 (0.89:0.95)
	MoCA	17.66 ± 6.15	12.91 ± 4.36	7.36 ± 4.77	75.54	62.30	15.5	0.73 (0.68:0.78)	77.88	89.53	10.5	0.90 (0.87:0.94)
Age ≤ 75 years and		N = 981	N = 183	N = 70
education > 6 years	MMSE	28.25 ± 2.01	25.04 ± 3.46	13.72 ± 8.61	74.47	57.49	28.5	0.71 (0.65:0.75)	88.52	97.03	23.5	0.95 (0.90:0.99)
	MoCA	25.79 ± 3.48	20.68 ± 4.16	9.14 ± 6.70	81.42	74.52	24.5	0.84 (0.81:0.87)**	90.00	97.35	18.5	0.97 (0.95:0.99)
Age > 75 years and		N = 324	N = 113	N = 38
education > 6 years	MMSE	27.01 ± 3.30	25.95 ± 3.68	14.10 ± 8.36	64.91	70.23	26.5	0.69 (0.62:0.77)	90.00	88.84	23.5	0.94 (0.89:0.99)
	MoCA	23.49 ± 4.80	20.68 ± 4.16	10.76 ± 6.45	86.37	53.87	24.5	0.72 (0.67:0.77)	84.21	89.47	20.5	0.94 (0.91:0.97)

MMSE, Mini-Mental State Examination; MoCA, Mini-Mental State Montreal Cognitive Assessment; MCI, mild cognitive impairment; AUC, area under the curve; CI, confidence interval. Bold indicates best performed for that indication; N = people who had complete data for all task.

^*p < 0.005,

^**p < 0.001.