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. 2021 Dec 2;12:780641. doi: 10.3389/fimmu.2021.780641

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Copyright © 2021 Rasmussen, Petersen and Eugen-Olsen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Levels of CRP, IL-6, and suPAR in the three inflammation groups identified by latent class analysis in the E-Risk study (n=1,390). Panels on the left show boxplots (box indicates median and interquartile range, and whiskers indicate 95% confidence interval) of untransformed C-reactive protein (CRP), interleukin-6 (IL-6), and soluble urokinase plasminogen activator receptor (suPAR) levels in the three groups, while the panel on the right shows mean Z-scores with standard deviations (M=0, SD=1). Group 1 (n=1,057) consisted of individuals with low CRP, IL-6, and suPAR. Group 2 (n=249) consisted of individuals with high CRP and IL-6 and moderately elevated suPAR. Group 3 (n=84) consisted of individuals with elevated CRP and IL-6 and high suPAR. Data from Rasmussen LJH, et al. (2020) (163).