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. 2021 Nov 30;23(1):94. doi: 10.3892/etm.2021.11017

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of the NLRP3 inflammasome inhibitor, Ac-YVAD-CMK on the contents of IL-1β and IL-18 in the culture media of human placental cells. ELISA was performed to determine the contents of IL-1β and IL-18 in the culture media. Ac-YVAD-CMK regulated the contents of (A) IL-1β and (B) IL-18 in the culture media. Data are presented as the mean ± SEM (n=4). ^**P<0.01. NLR family pyrin domain containing-3; Ac-YVAD-CMK, N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone; IL, interleukin; LG, low glucose; HG, high glucose.