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. 2021 Dec 1;23(1):99. doi: 10.3892/etm.2021.11022

Figure 4.

Figure 4

Effects of HOTAIR silencing and/or EZH2 overexpression on hBMVEC apoptosis. Evaluation of HBMVECs apoptosis using TUNEL assay. Magnification, x200. ***P<0.001 vs. Control, ###P<0.001 vs. OGD/R 24 h + siRNA-NC and ∆∆P<0.01 vs. OGD/R 24 h + siRNA-HOTAIR + Ov-NC. HOTAIR, Hox transcript antisense intergenic RNA; EZH2, enhancer of zeste homolog 2; si, small interfering RNA; OGD/R, oxygen-glucose deprivation/reperfusion; NC, negative control; Ov, overexpression; NC, negative control; hBMVECs, human brain microvascular endothelial cells.