Fig. 5. Accessibility of monoclonal antibody (mAb) epitopes of Bet v 1 bound to MSNPs (dark grey bars) and to NSNPs (light grey bars) in comparison to the unbound Bet v 1 control (black bars) determined by ELISA using (a) BIP 1, (b) #2, (c) #11, and (d) 5H8 anti-Bet v 1 mAbs. Values are expressed as % of mAb binding normalized to unbound Bet v 1. Values represent means of n = 3 with SD, statistical significance is indicated as ns p > 0.05, *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001, ****p ≤ 0.0001.