Table 2.
Results from main effect analyses in the whole brain (cluster-forming threshold Z > 3.09 and cluster-corrected P < 0.05.)
| Voxels | Z Max | X (mm) | Y (mm) | Z (mm) | Atlas labels |
|---|---|---|---|---|---|
| Main effect of temperature pooled groups | |||||
| 2676 | 7 | 42 | −12 | 8 | 83% central opercular cortex |
| 1605 | 4.86 | 0 | −74 | −14 | 100% vermis VI |
| 1292 | 6.09 | −36 | 4 | 8 | 66% central opercular cortex |
| 238 | 4.58 | 2 | −62 | 54 | 69% precuneus cortex |
| 166 | 4.87 | 24 | −40 | 70 | 39% superior parietal lobule and 33% postcentral gyrus |
| 156 | 4.19 | −20 | −84 | −38 | 100% left crus II |
| 121 | 4.48 | 0 | 30 | 28 | 70% cingulate gyrus, anterior division and 13% paracingulate gyrus |
| 90 | 4.23 | −54 | −30 | 18 | 70% parietal operculum cortex; 6% central opercular cortex; 6% supramarginal gyrus, anterior division; and 5% planum temporale |
| 85 | 4.81 | −48 | −66 | −30 | 81% left crus I |
| 84 | 4.53 | −4 | 22 | 44 | 78% paracingulate gyrus and 7% superior frontal gyrus |
| 79 | 4.73 | 2 | −10 | 44 | 73% cingulate gyrus, anterior division and 17% cingulate gyrus, posterior division |
| 77 | 4.16 | −50 | 44 | −10 | 83% frontal pole |
| 73 | 3.85 | −20 | −88 | −24 | 13% occipital fusiform gyrus and 66% left crus I |
| 72 | 4.11 | 16 | −14 | 6 | 97% right thalamus |
| 65 | 4.34 | 30 | −26 | 62 | 39% postcentral gyrus and 27% precentral gyrus |
| 62 | 3.93 | 4 | −6 | 12 | 34% left thalamus |
| 62 | 4.71 | −28 | −50 | −48 | 70% left VIIIa and 14% left VIIb |
| 58 | 3.98 | −38 | 62 | 8 | 54% frontal pole |
| 56 | 3.77 | −54 | −52 | 48 | 46% angular gyrus; 33% supramarginal gyrus, posterior division; and 5% lateral occipital cortex |
| Group differences in main effect of temperature (controls > patients) | |||||
| 124 | 3.98 | −22 | 60 | 18 | 71% frontal pole |
| 58 | 3.87 | 20 | 54 | 16 | 45% frontal pole |
| Main effect of task—pooled groups | |||||
| 4234 | 6.22 | −30 | −94 | 8 | 5% lateral occipital cortex |
| 3671 | 6.68 | 34 | −86 | 4 | 21% lateral occipital cortex, inferior division |
| 1147 | 6.27 | 8 | 28 | 30 | 48% paracingulate gyrus and 22% cingulate gyrus, anterior division |
| 887 | 5.47 | 32 | 24 | 2 | 54% frontal operculum cortex, 11% inferior frontal gyrus and pars opercularis, and 5% inferior frontal gyrus and pars triangularis |
| 382 | 5.53 | −30 | 28 | −2 | 54% insular cortex |
| 273 | 5 | −48 | 0 | 32 | 43% precentral gyrus, 12% middle frontal gyrus, and 11% inferior frontal gyrus and pars opercularis |
| 182 | 4.03 | −4 | −42 | −20 | 43% left I-IV |
| 156 | 4.26 | 28 | −52 | 54 | 43% superior parietal lobule and 12% angular gyrus |
| 155 | 4.96 | −8 | −70 | −16 | 98% left VI |
| 140 | 5.27 | 4 | −30 | −4 | 70.9% brainstem |
| 130 | 4.59 | −54 | −20 | 2 | 51% planum temporale and 10% Heschl gyrus (includes H1 and H2) |
| 104 | 4.25 | −8 | −74 | −38 | 64% left crus II and 31% left VIIb |
| 54 | 3.75 | −24 | −68 | −54 | 92% left VIIb |
| Negative main effect of task—pooled groups | |||||
| 691 | 4.59 | −6 | −60 | 30 | 62% precuneus cortex |
| 360 | 4.7 | −38 | −72 | 46 | 71% lateral occipital cortex, superior division |
| 248 | 4.95 | 52 | −62 | 42 | 66% lateral occipital cortex, superior division and 15% angular gyrus |
The tables were created with Autoaq (part of FSL), with atlas labels based on the degree of overlap with probabilistic atlases (Harvard Oxford Cortical Structural Atlas, Harvard Oxford Subcortical Structural Atlas, and Cerebellar Atlas in MNI152 space after normalization with FNIRT). Only those structures to which the cluster had a >5% chance of belonging to are presented.