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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Apr 20;148(3):895–901.e6. doi: 10.1016/j.jaci.2021.04.012

Figure 2: Functional impact of cytokine release.

Figure 2:

A: Representative histograms showing p-STAT3 in identified subsets at baseline (blue) and 4 h after symptoms (orange) as measured by mass cytometry. B: summary data of median intensity of STAT3 in cell subsets before and after challenge, in those with active (n=4) or outgrown (n=3) FPIES. C: Expression of IL-17A target genes measured by RNA sequencing of whole blood obtained before or after FPIES challenge. Each dot indicates one patient. *p<0.05 by paired analysis.