TABLE 3.
Significantly changed metabolites between different groups.
| No | Metabolites | OVX/sham | OVX-XSH/OVX | ||||||
|---|---|---|---|---|---|---|---|---|---|
| log2(FC) | −log10(p) | VIP | Trend | log2(FC) | −log10(p) | VIP | Trend | ||
| 1 | l-Cystine | −0.68 | 3.62 | 1.25 | down | 0.74 | 4.09 | 1.37 | up |
| 2 | l-Lactic acid | −1.26 | 5.91 | 1.34 | down | 1.29 | 4.70 | 1.36 | up |
| 3 | l-Alanine | −2.04 | 5.72 | 1.39 | down | 2.04 | 4.44 | 1.38 | up |
| 4 | Epinephrine | 0.46 | 3.50 | 1.18 | up | −0.67 | 4.32 | 1.33 | down |
| 5 | 4-Hydroxybutyric acid | — | — | — | — | 0.83 | 2.83 | 1.01 | up |
| 6 | l-Valine | −1.46 | 4.60 | 1.37 | down | 1.49 | 3.94 | 1.37 | up |
| 7 | Urea | −0.86 | 3.94 | 1.25 | down | 0.44 | 1.55 | 1.08 | up |
| 8 | l-Proline | −1.61 | 4.39 | 1.36 | down | 1.63 | 3.75 | 1.34 | up |
| 9 | l-Serine | −0.95 | 3.80 | 1.30 | down | 0.91 | 2.90 | 1.28 | up |
| 10 | l-Threonine | −1.16 | 4.38 | 1.26 | down | 0.49 | 1.55 | 1.06 | up |
| 11 | l-Asparagine | −0.89 | 3.25 | 1.22 | down | — | — | — | — |
| 12 | d-Arabinose | 0.86 | 2.47 | 1.02 | up | −1.00 | 2.99 | 1.17 | down |
| 13 | N-Acetylneuraminic acid | −2.32 | 5.83 | 1.38 | down | 2.47 | 4.70 | 1.37 | up |
| 14 | l-Glutamine | −1.05 | 3.54 | 1.27 | down | 1.04 | 3.05 | 1.33 | up |
| 15 | d-Galactose | −0.59 | 4.38 | 1.26 | down | 0.57 | 2.58 | 1.14 | up |
| 16 | l-Lysine | −1.58 | 4.27 | 1.33 | down | 1.19 | 2.52 | 1.21 | up |
| 17 | d-Glucose | −0.85 | 2.80 | 1.19 | down | 0.75 | 2.27 | 1.18 | up |
| 18 | l-Tyrosine | −0.41 | 1.94 | 1.02 | down | 0.53 | 1.92 | 1.12 | up |
| 19 | d-Xylulose | −1.24 | 3.30 | 1.24 | down | 1.24 | 2.99 | 1.26 | up |
| 20 | Stearic acid | −0.29 | 3.27 | 1.14 | down | — | — | — | — |
| 21 | L-Tryptophan | −1.14 | 5.21 | 1.32 | down | 0.78 | 2.25 | 1.08 | up |