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Tissue-to-plasma concentration ratios of escitalopram (A,B) and paroxetine (C,D) in the brain and lungs up to 480 min after intravenous (IV), intranasal (IN), and IN delivery of BorNLC (IN + BorNLC) co-administration (2.38 mg/kg) to mice. Two-way analysis of variance (ANOVA) with multiple comparison test was performed, *p < 0.05, **p < 0.01, and ***p < 0.001.
