TABLE 2.

Full meta‐analytic results for volume and thickness of each bilateral structure for the alcohol use disorder versus controls comparison controlling for age, sex and intracranial volume (for subcortical regions only)

ROI	ES	SE	95% CI.LB	95% CI.UB	I 2	p	p FDR	Controls	Cases
Thalamus	−0.2272	0.0976	−0.4184	−0.0359	28.84	.0199	.0279	359	345
Caudate	−0.0382	0.094	−0.2225	0.1461	28.12	.6844	.6844	361	437
Putamen	−0.2656	0.0966	−0.455	−0.0762	30.53	.006	.0105	361	436
Pallidum	−0.1002	0.0727	−0.2427	0.0423	0.01	.1681	.1961	365	437
Hippocampus	−0.5037	0.1325	−0.7634	−0.244	60.85	.0001	.0010	362	437
Amygdala	−0.3942	0.1215	−0.6323	−0.156	53.99	.0012	.0031	364	437
Accumbens	−0.3044	0.0948	−0.4901	−0.1187	28.27	.0013	.0031	362	436
Bankssts	−0.15	0.147	−0.43	0.14	68.609	.319	.5784	360	436
Caudalanteriorcingulate	−0.24	0.073	−0.38	−0.09	0.00	.001	.0067	365	437
Caudalmiddlefrontal	−0.1	0.154	−0.4	0.2	71.767	.517	.7563	365	437
Cuneus	−0.03	0.142	−0.31	0.25	66.9	.817	.9496	364	437
Entorhinal	−0.22	0.137	−0.48	0.05	62.843	.115	.3001	362	431
Fusiform	−0.47	0.084	−0.64	−0.31	14.048	.00	.0001	365	436
Inferior parietal	−0.01	0.149	−0.3	0.29	70.21	.965	.9647	365	437
Inferior temporal	−0.36	0.081	−0.52	−0.21	10.367	.00	.0001	365	437
Isthmus cingulate	−0.22	0.103	−0.43	−0.02	37.955	.029	.0997	364	436
Lateral occipital	−0.16	0.119	−0.39	0.08	52.71	.188	.4576	365	437
Lateral orbitofrontal	−0.29	0.119	−0.53	−0.06	52.526	.014	.0531	365	436
Lingual	−0.01	0.143	−0.29	0.27	67.39	.942	.9647	365	437
Medial orbitofrontal	−0.13	0.116	−0.36	0.1	49.999	.265	.5630	364	436
Middle temporal	−0.23	0.137	−0.49	0.04	63.939	.1	.2833	361	437
Parahippocampal	−0.25	0.073	−0.39	−0.1	0.003	.001	.0053	364	437
Paracentral	−0.19	0.196	−0.58	0.19	82.825	.323	.5784	365	437
Pars opercularis	−0.01	0.131	−0.27	0.24	61.005	.921	.9647	365	437
Pars orbitalis	−0.06	0.109	−0.28	0.15	43.834	.556	.7563	365	437
Pars triangularis	−0.03	0.167	−0.36	0.29	76.22	.839	.9496	365	437
Pericalcarine	0.05	0.166	−0.28	0.37	75.831	.781	.9496	365	436
Postcentral	0.05	0.203	−0.35	0.45	84.059	.809	.9496	365	437
Posterior cingulate	−0.29	0.115	−0.51	−0.06	49.129	.012	.0498	365	437
Precentral	−0.13	0.189	−0.5	0.24	81.542	.503	.7563	365	437
Precuneus	−0.15	0.14	−0.43	0.12	66.082	.284	.5686	365	437
Rostralanteriorcingulate	−0.31	0.073	−0.45	−0.17	0.001	.000	.0002	365	437
Rostral middle frontal	−0.03	0.178	−0.38	0.32	79.1	.866	.9496	365	437
Superior frontal	−0.18	0.073	−0.33	−0.04	0.002	.011	.0498	365	436
Superior parietal	−0.11	0.186	−0.47	0.25	80.83	.549	.7563	365	436
Superior temporal	−0.21	0.182	−0.57	0.14	79.566	.242	.5483	360	435
Supramarginal	−0.14	0.148	−0.43	0.15	69.05	.344	.5853	361	436
Frontal pole	0.06	0.073	−0.08	0.2	0.00	.408	.6611	365	437
Temporal pole	−0.32	0.073	−0.46	−0.17	0.00	.00.	.0002	365	437
Transverse temporal	0.05	0.152	−0.25	0.34	71.255	.76	.9496	365	437
Insula	−0.21	0.12	−0.45	0.03	53.324	.08	.2471	363	436

Abbreviations: Bankssts, banks of the superior temporal sulcus; CI.LB, confidence interval lower bound; CI.UB, confidence interval upper bound; ES, effect size; p _FDR, adjusted p‐value for the seven sites following a BH correction; ROI, region of interest.

P_FDR less than 0.05 are in bold.