. 2020 Apr 20;43(1):129–148. doi: 10.1002/hbm.25015

TABLE 2.

Data elements collected by the ENIGMA Stroke Recovery working group

	MRI	Behavior	Demographics
Required	T1‐weighted structural MRI Scanner strength, brand, and model Alternative if unable to share raw T1 MRIs: A spreadsheet with FreeSurfer cortical and subcortical measurements, quality control 2D image slices, and lesion masks (registered to a standardized template)	At least 1 behavioral outcome measure Most common measures at time of publication: Fugl‐Meyer Assessment (72%) NIH Stroke Scale (19%) Motor Activity Log (16%) Modified Ashworth (12%) Action Research Arm Test (11%) Wolf Motor Function Test (9%)	None required Most common demographics at time of publication: Age Sex Time since stroke/last known well (in days) Lesioned hemisphere
Recommended	FLAIR Diffusion MRI Resting‐state fMRI Lesion masks Longitudinal scans EEG	We suggest collecting measures recommended by the Stroke Recovery and Rehabilitation Roundtable (Bernhardt et al., 2017) Current recommendations for sensorimotor outcomes can be found in Kwakkel et al. (2017) Current recommendations for cognitive outcomes can be found in McDonald et al. (2019)	First stroke or multiple strokes Race/ethnicity Hand dominance prior to stroke Therapy received (hours per week) Risk factors for cardiovascular disease (e.g., hypertension, obesity, diabetes smoking) Dementia status Comorbidities

MRI

Behavior

Demographics

Required

T1‐weighted structural MRI

Scanner strength, brand, and model

Alternative if unable to share raw T1 MRIs:

A spreadsheet with FreeSurfer cortical and subcortical measurements, quality control 2D image slices, and lesion masks (registered to a standardized template)

At least 1 behavioral outcome measure

Most common measures at time of publication:

Fugl‐Meyer Assessment (72%)
NIH Stroke Scale (19%)
Motor Activity Log (16%)
Modified Ashworth (12%)
Action Research Arm Test (11%)
Wolf Motor Function Test (9%)

None required

Most common demographics at time of publication:

Age
Sex
Time since stroke/last known well (in days)
Lesioned hemisphere

Recommended

FLAIR
Diffusion MRI
Resting‐state fMRI
Lesion masks
Longitudinal scans
EEG

We suggest collecting measures recommended by the Stroke Recovery and Rehabilitation Roundtable (Bernhardt et al., 2017)

Current recommendations for sensorimotor outcomes can be found in Kwakkel et al. (2017)

Current recommendations for cognitive outcomes can be found in McDonald et al. (2019)

First stroke or multiple strokes
Race/ethnicity
Hand dominance prior to stroke
Therapy received (hours per week)
Risk factors for cardiovascular disease (e.g., hypertension, obesity, diabetes smoking)
Dementia status
Comorbidities

Note: The data elements are divided into three main components: MRI, behavioral measures, and demographic data, and further separated into required versus recommended elements.