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. 2021 Dec 16;21:347. doi: 10.1186/s12866-021-02411-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Reduction of P. aeruginosa biofilm formation by combination of ceftazidime (1/16× MIC) and different concentrations of cellulase in PAO1, PA1, and PA2. The error bars indicate the standard deviations between strains. The microplates were incubated for 24 h at 37 °C. Data were normalized to the mean value of the control, which was set at 100%. The error bars indicate the standard deviations between bacteria. Results were expressed as percentage of biofilm biomass formed with respect to control. The statistical significance of the data was determined by an analysis of variance (ANOVA) test followed by the Tukey-Kramer multiple comparison test. Significance was accepted when the P-value was < 0.05 (****P < 0.0001). MIC: Minimum inhibitory concentration