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. Author manuscript; available in PMC: 2021 Dec 16.
Published in final edited form as: Annu Rev Cell Dev Biol. 2020 Oct 6;36:35–60. doi: 10.1146/annurev-cellbio-032320-094706

Figure 2. Cooperative and Competitive Interactions in F-Actin Networks in Animal and Fission Yeast:

Figure 2.

To self-organize multiple functionally diverse F-actin networks simultaneously from a common pool of components, both animal and fission yeast cells must (A) properly allocate actin monomers between competing networks, and (B) sort unique subsets of actin-binding proteins, which establish the structure and dynamics of each network. (C) ABPs compete and cooperate with each other, leading to a potential ABP hierarchy, where upstream proteins either recruit or inhibit the access of downstream proteins to specific F-actin networks.