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. 2021 Dec 2;12:745049. doi: 10.3389/fneur.2021.745049

Table 2.

Changes in weight and HbA1c of the analyzed 346 subjects within the observation period of 2.3 (2.2;2.4) years.

Total sample SDB PAP SDB untreated p-value
n (%) 346 (100) 60 (17.3) 286 (82.7)
Weight change (kg) −0.8(−3.2; 1.3)a −0.2 (−3.2; 2.6) −0.9 (−3.2; 1.3) 0.322
Weight gain ≥ 5 kg, n (%) 25 (7.2) 9 (15.0) 16 (5.6) 0.011
Weight loss ≥ 5 kg, n (%) 50 (14.5) 8 (13.3) 42 (14.7) 0.787
Change in BMI (kg/m2) −0.3 (−1.1; 0.5)a −0.1 (−1.1; 0.9) −0.3 (−1.1; 0.5)a 0.353
Increase in BMI ≥ 2 kg/m2, n (%) 16 (4.6) 6 (10.0) 10 (3.5) 0.029
Decrease in BMI ≥ 2 kg/m2, n (%) 40 (11.6) 7 (11.7) 33 (11.5) 0.977
Change in HbA1c (mmol/mol) 1 (−4; 5) 3 (−2; 7)a 0 (−4; 5) 0.020
Change in HbA1c (%) 0.1 (−0.4; 0.5) 0.3 (−0.2; 0.7)a 0.0 (−0.4; 0.5) 0.023
Increase in HbA1c ≥ 1%, n (%) 30 (8.7) 7 (11.7) 23 (8.1) 0.369
Decrease in HbA1c ≥ 1%, n (%) 29 (8.4) 2 (3.3) 27 (9.5) 0.119

Results are provided as median with interquartile ranges for continuous variables and absolute value (%) for categorical variables.

BMI, body-mass index; HbA1c, hemoglobin A1c; PAP, positive airway pressure; SDB, sleep-disordered breathing.

a

Significant change to baseline.

The bold values are p-values < 0.05.