Table 4.
Multivariable regression analysis with known potential modulators for weight gain ≥5 kg and change in HbA1c within the observation period in 346 patients with type 2 diabetes mellitus.
| Weight gain ≥ 5 kg | Change in HbA1c (mmol/mol) | |||
|---|---|---|---|---|
| OR (95% CI) | p-value | B (95% CI) | p-value | |
| HbA1c (mmol/mol) | 1.036 (1.006; 1.068) | 0.019 | −0.297 (−0.375; −0.220) | <0.001 |
| Insulin substitution (yes vs. no) | 0.896 (0.362; 2.222) | 0.813 | 2.374 (0.554; 4.194) | 0.011 |
| BMI (kg/m2) | 0.999 (0.914; 1.093) | 0.989 | −0.016 (−0.179; 0.146) | 0.845 |
| Waist-hip ratio (%) | 1.064 (0.996; 1.137) | 0.066 | 0.022 (−0.101; 0.146) | 0.720 |
| Low physical activity | 1.534 (0.618; 3.807) | 0.356 | 0.349 (−1.378; 0.190) | 0.691 |
| Apnea-hypopnea-index (/h) | 0.987 (0.955; 1.021) | 0.455 | −0.005 (−0.071; 0.062) | 0.893 |
| PAP treatment (yes vs. no) | 3.497 (1.343; 9.106) | 0.010 | 2.410 (0.118; 4.702) | 0.039 |
Shown are the unstandardized regression coefficients by regression analysis, 95% CI and p-values.
BMI, body-mass index; HbA1c, hemoglobin A1c; PAP, positive airway pressure; SDB, sleep-disordered breathing; low physical activity = exercise <3 × /wk.
The bold values are p-values < 0.05.