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. 2021 Dec 2;9:770049. doi: 10.3389/fbioe.2021.770049

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Copyright © 2021 Li, Wang, Li, Song, Lei, Gui, Zhou and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vivo sample staining results. (A) Histological analysis of bone defects repaired by each group at weeks 4 and 8 after surgery (bar = 200 μm). (B) The percentage of the new bone area and (C) the density of neovascularization in the repaired bone defect area in each group at weeks 4 and 8 after surgery. ***p < 0.001.