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Graphs of ELISpot disk counts comparing vaccinations of our TF-Ser(5)-MUC4-B13G-AuNP conjugate the TF-Ser(5)-MUC4-CRM197 conjugate and control B13G-AuNPs when panned for interferon-γ and IL-17 production. While the TF-Ser(5)-MUC4-CRM197 conjugate has an intense humoral response, the TF-MUC4 vaccine construct elicited a much stronger CD4+ T-cell response, whereas the control B13G-AuNPs consistently showed no response.
