Table 5.

Width, Height and Thickness details for defining and delineating four categories of CTV-T_HR-CT based on MR at diagnosis & Pre BT MR and CT at BT (MRI_DG - Pre BT MRI and CT_BT Environment).

Cat of BT	Width	Height		Thickness
	Lateral	Superior	Inferior	Anterior	Posterior
IBT	Lateral boundaries of cervix	To review upper extent of disease on MR at diagnosis and Pre BT MR with respect to landmark anatomical structures eg. Uterine arteries, isthmus, distances from the surface of fundus etc. and extrapolate on CT at BT* * may not be applicable in enlarged uterine cavity due to fluid collection.	Lower extent of cervical lip with vaginal applicator as surrogate	Outer surface of the cervix &/or uterus guided by Pre BT MR dimensions	Outer surface of the cervix &/or uterus guided by Pre BT MR dimensions
IIBT	Proximal parametrium defined by clinical/TRUS based NMD’s (if available) and guided by NMD’s on Pre-BT MR including gray zones		Review Pre-BT MR and include appropriate length of vaginal wall defined by clinical examination, with /without guidance of markers implanted and the Pre BT MR findings, with few mm safety margins longitudinal and circumferential.
				To utilize TRUS based distances (if available)	To utilize TRUS based distances (if available)
IIIBT	Distal parametrium defined by clinical/TRUS based NMD’s (if available) and guided by NMD’s on Pre-BT MR including gray zones
IVBT	Proximal /distal parametrium/Up to lateral pelvic wall defined by clinical/TRUS based NMD’s (if available) and guided by NMD’s on Pre-BT MR including gray zones			In addition to outer surface of the cervix &/or uterus to include the bladder wall/mucosae involved with 2 cm margins at least guided by Pre BT MR findings To utilize TRUS based distances (if available)	In addition to outer surface of the cervix &/or uterus to include the rectal wall/mucosae involved with 2 cm margins at least guided by Pre BT MR findings
					To utilize TRUS based distances (if available)