Table 1.

Most used creatinine and cystatin C equations to estimate glomerular filtration rate (eGFR).

Cockcroft-Gault equation

Creatinine Clearance = $\frac{140-\text{age }(\text{years})\text{ x weight }(\text{kg})}{72\text{ x serum creatinine }(\text{mg}/\text{dl})}\text{ x }0.85(\text{if female})$

MDRD-4 (simplified) Estimated Glomerular Filtration Rate (mL/min/1.73 m2) == 175 (Serum Creatinine in mg/dl × 0.011312)−1.154 × (age in years )−0.203 × (0.742 if female) × (1.212 if African American/black)

CKD-EPI (2009) Estimated GFR = 141 x min(SCr/κ, 1)α x max(SCr /κ, 1)−1.209 x 0.993Age x 1.018 [if female] x 1.159 [if Black] SCr (standardized serum creatinine) = mg/dL., K = 0.7 (females) or 0.9 (males), α = −1.329 (female) or−0.411 (male), Min = indicates the minimum of SCr/K or 1, max = indicates the maximum of SCr/K or 1, Age = Years

FAS (2016)1) Estimated GFR = 107.3/(SCr/ Q) for age ≤ 2 to ≤ 40 years 2) Estimated GFR = 107.3/(Scr/ Q) x 0.988 (age−40) for age > 40 years Q: the mean or median SCr value for age/sex-specific healthy populations

CKD-EPI cystatin C equation Estimated Glomerular Filtration Rate (mL/min/1.73 m2) == 133 × min(Scys/0.8, 1)−0.499 × max (Scys/0.8, 1)−1.328 × 0.996Age [ × 0.932 if female] Scys = serum cystatin C, min indicates the minimum of Scr/κ or 1, and max indicates the maximum of Scys/κ or 1

CKD-EPI creatinine-cystatin C Estimated Glomerular Filtration Rate (mL/min/1.73 m2) =135 × min(Scr/κ, 1)α × max(Scr/κ, 1)−0.601 × min(Scys/0.8, 1)−0.375 × max(Scys/0.8, 1)−0.711 ×0.995Age [ ×0.969 if female] [ ×1.08 if black]Scr = serum creatinine, Scys = serum cystatin C, κ is 0.7 for females and 0.9 for males, α is −0.248 for females and −0.207 for males, min indicates the minimum of Scr/κ or 1, and max indicates the maximum of Scr/κ or 1.