Table 2.

Effect of base and solvents in the Suzuki coupling reaction

Entry	Base	Solvents*	Yielda, %	Yieldb, %
1	NaOH	CH3 CH2 OH	97.36	97.20
2	KOH	CH3 CH2 OH	98.01	96.79
3	K2 CO3	CH3 CH2 OH	98.66	98.19
4	K3 PO4 ·3H2 O	CH3 CH2 OH	98.69	97.25
5	NaOAc	CH3 CH2 OH	87.25	86.26
6	NH3 ·H2 O	CH3 CH2 OH	36.26	22.64
7	Et3 N	CH3 CH2 OH	62.64	87.65
8	K2 CO3	CH3 OH	98.73	98.00
9	K2 CO3	THF	42.92	24.94
10	K2 CO3	DMF	33.06	24.43
11	K2 CO3	DMAc	29.47	32.69
12	K2 CO3	Toluene	20.81	12.23

Reaction conditions: 4‐bromotoluene (5.0 mmol), phenylboronic acid (7.5 mmol), Pd NPs (0.5 mmol ‰), base (10.0 mmol), solvent/H₂ O (25 ml/25 ml) at 60°C for 30 min.

^a Pd‐LDHs‐B.

^b Pd‐LDHs‐P.

*The different organic reagents added in the mixture containing 1:1 volume ratio of H₂ O and organic reagents are only listed.