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. 2016 Jun 29;2016(6):CD006837. doi: 10.1002/14651858.CD006837.pub3

Baum 1997.

Methods Randomization and treatment allocation method: yes
Blinding of outcome assessment: yes
Blinding of participants: no
Study period: not stated
Participants Number: 46 enrolled
Inclusion criteria: un‐pre‐medicated paediatric patients (6 months to 8 years) scheduled for elective ambulatory surgery under general anaesthesia who had ASA physical status I to II, no known reactive airway, no history of malignant hyperthermia
Exclusion criteria: not stated
Interventions All groups received 70% N2O with total flow 6 LPM, tidal volume breathing technique and paediatric circle circuit
Group 1: 8% sevoflurane with priming technique
Group 2: incremental sevoflurane
Group 3: incremental halothane
Outcomes Time to complete calmness
Time to eye closure
Child’s distress (modified Observation Scale of Behavioral Distress)
Complication
Notes Location: USA
Setting: operating room
Source of funding: Abbott Laboratories
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "Patients had anaesthesia induced by one of three methods, as assigned by means of a table of random numbers"
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement
Blinding (performance bias and detection bias) 
 All outcomes Low risk Quote: "Video recordings were analysed off‐line by a different paediatric anaesthesiologist"
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing data
Selective reporting (reporting bias) Low risk Study authors reported all planned outcomes