Table 3.
Physicochemical properties of DOX loaded PMVEMA NPs
| Formulation code | Particle size, nm | Zeta potential, mV | Drug loading efficiency, % | Drug release efficiency (RE72 %) |
|---|---|---|---|---|
| D2.5 Zn50 R960 | 247.50 ± 9.03 | −23.1 ± 1.2 | 92.74 ± 5.26 | 27.73 ± 1.54 |
| D2.5 Zn25 R960 | 261.83 ± 30.60 | −38.0 ± 2.3 | 90.70 ± 1.78 | 37.69 ± 2.23 |
| D2.5 Zn25 R1200 | 227.67 ± 11.62 | −28.9 ± 1.5 | 92.59 ± 4.41 | 30.14 ± 2.41 |
| D2.5 Zn50 R1200 | 162.96 ± 1.60 | −32.0 ± 0.4 | 90.79 ± 1.14 | 26.61 ± 3.27 |
| D5 Zn25 R1200 | 285.26 ± 26.25 | −31.4 ± 1.7 | 91.39 ± 1.79 | 22.14 ± 2.12 |
| D5 Zn50 R1200 | 178.20 ± 24.15 | −30.1 ± 3.7 | 91.48 ± 0.47 | 23.86 ± 2.31 |
| D5 Zn25 R960 | 223.80 ± 1.91 | −32.8 ± 0.6 | 91.74 ± 0.71 | 20.77 ± 3.11 |
| D5 Zn50 R960 | 149.90 ± 5.31 | −28.2 ± 2.0 | 90.77 ± 0.34 | 22.55 ± 2.95 |