Table 1.
Glucose level of the experimental animals treated with ZnO NPs
| Group I (control) | Group II (diabetic control) | Group III (positive control – glibenclamide) | Group IV (ZnO NPs 5 mg/kg b.wt) | Group V (ZnO NPs 10 mg/kg b.wt) | |
|---|---|---|---|---|---|
| initial day (mg/dl) | 90.50 ± 8.78 | 380.33 ± 38.15 a** | 349.83 ± 30.89 a** | 329.33 ± 34.27 a** | 337.67 ± 19.37 a** |
| 7th day (mg/dl) | 95.00 ± 10.05 | 422.83 ± 23.31 a** | 152.67 ± 18.19 b** | 197.83 ± 8.03 a**b** | 237.67 ± 13.22 a**b** |
| 14th day (mg/dl) | 80.17 ± 8.27 | 409.50 ± 43.32 a** | 121.33 ± 9.97 b** | 219.33 ± 13.70 a** b** | 205.33 ± 20.94 a** b** |
| 21st day (mg/dl) | 80.83 ± 11.09 | 423.50 ± 23.91 a** | 119.50 ± 9.91 b** | 194.16 ± 7.87 a** b** | 189.167 ± 6.88 a** b** |
| 28th day (mg/dl) | 100.83 ± 6.18 | 383.00 ± 27.57 a** | 116.16 ± 5.12 b** | 193.83 ± 5.74 a** b** | 179.00 ± 7.48 a* b** |
Values are mean±SEM, n = 6, * p < 0.05, ** p < 0.01. Statistical analysis – ANOVA followed by Tukey's comparison test. a: comparison of group I with other groups and b: comparison of group II with other groups.