Table 1.
First author, year | Reference no. | Intervention | Sample size | Age | Duration | Outcome | |||
---|---|---|---|---|---|---|---|---|---|
Treatment | Control | Treatment | Control | Treatment | Control | ||||
Sun T, 2012 | [14] | Aspirin + ozagrel + Ginkgo dameer | Aspirin + ozagrel | 40 | 40 | 66.5 | 64.8 | 2 weeks | a, b |
Zhou YF, 2016 | [15] | Routine + shuxuening | Routine | 63 | 63 | 68.3 ± 8.5 | 67.1 ± 7.9 | 2 weeks | a, b, c |
Shi YF, 2017 | [16] | Routine + aspirin + ginkgo ester dispersive tablets | Routine + aspirin | 41 | 41 | 69.42 ± 7.24 | 68.72 ± 8.14 | 2 weeks | d, e |
Wang LM, 2017 | [17] | Edaravone + propranolol + aspirin + mannitol + furosemide + Ginkgo biloba leaf extract | Edaravone + propranolol + aspirin + mannitol + furosemide | 73 | 73 | 59.48 ± 13.24 | 58.91 ± 13.07 | 4 weeks | d, f |
Yang T, 2017 | [18] | Routine + alprostadil + ginkgo ester dispersive tablets | Routine + alprostadil | 49 | 49 | 68.9 + 1.7 | 68.2 ± 1.6 | 2 weeks | d, f |
Zhou G, 2018 | [19] | Routine + rosiglitazone + ginkgo ester dispersive tablets | Routine + rosiglitazone | 51 | 51 | 53.64 ± 10.25 | 53.72 ± 10.38 | 4 weeks | a, b, d, e |
Zhou QW, 2019 | [20] | Rt-PA + ginkgolide injection | Rt-PA | 44 | 43 | 63.08 ± 7.18 | 62.97 ± 7.25 | 2 weeks | a, b |
Chen E, 2020 | [21] | Mannitol + aspirin + mecobalamin + ginkgo ester dropping pills | Mannitol + aspirin + mecobalamin | 50 | 50 | 53.10 ± 10.39 | 52.39 ± 10.23 | 2 weeks | d, e |
Xiao H, 2020 | [22] | Butylphthalide + ginkgo diterpene lactone glutamine | Butylphthalide | 41 | 41 | 62.15 ± 6.45 | 61.37 ± 6.44 | 2 weeks | a, b |
Wu Y, 2020 | [23] | Routine + ginkgolide injection | Routine treatment | 46 | 46 | 68.9 + 1.7 | 68.2 ± 1.6 | 2 weeks | d, f |
Zhang DN, 2020 | [24] | Routine + butylphthalide + ginkgolide injection | Routine + butylphthalide | 39 | 39 | 61.98 ± 7.65 | 61.82 ± 7.51 | 4 weeks | a, b, c, f |
Shi XJ, 2021 | [25] | Routine + Butylphthalide injection + diterpene lactone Ginkgo biloba injection | Routine + Butylphthalide injection | 63 | 63 | 65.13 ± 7.29 | 64.23 ± 6.18 | 2 weeks | b, c, d, |
Zhang TT, 2021 | [26] | Rt-PA + Ginkgo biloba extract injection | Rt-PA | 30 | 30 | 56.28 ± 5.09 | 56.91 ± 5.38 | 1 week | a, b, c, e, f |
Outcomes: (a) NIHSS; (b) clinical therapeutic effect; (c) BI; (d) plasma viscosity; (e) fibrinogen; (f) adverse reactions.