TABLE 2.
Antifungal agent | % Agreementa
|
|||||||
---|---|---|---|---|---|---|---|---|
C. albicans (n = 14) | C. glabrata (n = 10) | C. tropicalis (n = 10) | C. krusei (n = 10) | C. dubliniensis (n = 10) | C. parapsilosis (n = 10) | C. neoformans (n = 10) | Overallb (n = 74) | |
Amphotericin B | 100 | 100 | 100 | 100 | 60 | 90 | 70 | 89 |
Flucytosine | 93 | 100 | 70 | 100 | 80 | 60 | 60 | 80 |
Fluconazole | 78 | 90 | 70 | 100 | 100 | 100 | 100 | 91 |
Ketoconazole | 71 | 80 | 80 | 100 | 100 | 100 | 90 | 89 |
Terconazole | 71 | 90 | 80 | 30 | 100 | 70 | 100 | 77 |
Itraconazole | 64 | 80 | 90 | 90 | 90 | 80 | 100 | 85 |
Miconazole | 43 | 70 | 40 | 100 | 60 | 50 | 100 | 66 |
Clotrimazole | 29 | 30 | 0 | 60 | 100 | 50 | 0 | 53 |
Overall agreement (eight drugs) | 69 | 80 | 66 | 85 | 86 | 75 | 90 | 79 |
Overall agreement (without miconazole and clotrimazole) | 80 | 90 | 82 | 87 | 88 | 83 | 87 | 85 |
Percent agreement between results defined as proportion of MICs determined by the PASCO method that were within ±2 twofold serial dilutions of the MICs determined by the standard NCCLS M27-A method.
Percent agreement between the MICs determined by the PASCO and M27-A methods for all isolates for each drug tested.