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. 2021 Sep;42(5):378–385. doi: 10.2500/aap.2021.42.210065

Table 2.

Global estimates of annual vaccine-preventable deaths in children < 5 years of age in order of prevalence of deaths*

graphic file with name OC-AAPJ210065T002.jpg

Causal organism No. Deaths
(1) Streptococcus pneumoniae 294,000
(2) Rotavirus 215,000
(3) Bordetella pertussis 161,000
(4) Measles virus 74,015
(5) Haemophilus influenzae type b 29,500
(6) Influenza virus 28,000–111,500#

*Adapted from Ref. 2.

#

Year-to-year variation.