Table 6.
Final Hazard Ratio Estimates and 95% Confidence Intervals (CI) Based on Multivariate Cox Models for Recurrent Events Estimating Risk Factors Associated With Repeated Occurrence of Ebola Virus Disease Sequelae After Ebola Treatment Center Discharge
| Abdominala sequelae | Neurologicalb sequelae | Ocularc sequelae | Musculoskeletald sequelae | Generale sequelae | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms of the acute phase | HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value |
| Sex (male) | 1.24 (0.58–2.61) | .581 | 1.28 (0.51–3.21) | .600 | 1.09 (0.60–1.97) | .781 | 0.62 (0.32–1.20) | .156 | 0.71 (0.25–1.95) | .503 |
| Age (Linear Trend) | 1.06 (0.89–1.25) | .515 | 1.61 (0.68–3.81) | .280 | 1.12 (1.01–1.27) | .045 | 1.15 (1.05–1.26) | .002 | 1.27 (1.00–1.62) | .048 |
| Age2 (QuadraticTrend) | 0.99 (0.99–1.01) | .602 | 0.71 (0.46–1.11) | .140 | 0.99 (0.99–1.00) | .117 | 0.99 (0.99–1.00) | .013 | 0.99 (0.99–1.00) | .099 |
| General | 0.32 (0.11–0.94) | .038 | 1.12 (0.35–3.62) | .840 | 0.34 (0.18–0.64) | .003 | 0.60 (0.32–1.12) | .110 | 0.56 (0.21–1.50) | .250 |
| Hemorrhage | 0.81 (0.32–2.02) | .650 | 0.55 (0.19–1.59) | .270 | 2.70 (1.31–5.60) | .007 | 1.91 (1.02–4.06) | .045 | 0.91 (0.27–3.06) | .888 |
| Abdominala | 1.70 (0.67–4.28) | .260 | 2.00 (0.64–6.27) | .240 | 1.27 (0.62–2.62) | .509 | 2.21 (1.06–4.58) | .033 | 1.84 (0.52–6.53) | .343 |
| Myalgia | 1.92 (0.80–4.61) | .144 | 0.83 (0.32–2.13) | .700 | 0.96 (0.46–1.97) | .902 | 0.68 (0.32–1.40) | .294 | 5.04 (1.52–16.75) | .008 |
| Neurologicalb | 2.28 (0.75–6.91) | .143 | 1.39 (0.39–4.99) | .610 | 2.63 (1.15–6.01) | .021 | 1.07 (0.47–2.43) | .871 | 0.34 (0.10–0.98) | .049 |
Recurrent events refer to events of interest experienced repeatedly by a given individual.
Abbreviation: HR, hazard ratio.
aAbdominal = abdominal or pelvic pain, gastritis.
aNeurological = headache, dizziness and other (neurosensitive disorders, neuromotor disorders, behavioral problems).
aOcular = conjunctivitis, iridocyclitis, cataract, glaucoma, vision problems, ocular pain.
aMusculoskeletal = neck pain, back pain, joint pain, myalgia.
aGeneral = fever, fatigue, anorexia.