Table 3.
Clinical course and outcome of GBS in relation to SARS-CoV-2 infection
| SARS-CoV-2 confirmed/probablea |
||||
|---|---|---|---|---|
| Total (n = 49) | Yes (n = 11) | No (n = 36) | P-value | |
| Mortality (%) | 3/46 (7) | 2 (18) | 1/34 (3) | 0.14 |
| Mechanical ventilation (%) | 9/47 (19) | 4 (36) | 5/34 (15) | 0.19 |
| Days of ventilation (IQR) | 17 (10–31) n = 7 | 31 (17–31) n = 2 | 11 (7–25) n = 5 | 0.25 |
| ICU admission (%) | 13/47 (28) | 6 (55) | 7/34 (21) | 0.05 |
| Days in ICU (IQR) | 14 (3–31) n = 12 | 28 (7–40) n = 5 | 3 (3–24) n = 7 | 0.09 |
| Week 4 | ||||
| MRC sum score (IQR) | 54 (32–60) n = 30 | 49 (21–60) n = 8 | 55 (41–60) n = 22 | 0.28 |
| GBS disability score (%) | ||||
| 0–2 | 16/31 (52) | 3/8 (38) | 13/23 (57) | 0.43 |
| 3–4 | 12/31 (39) | 3/8 (38) | 9/23 (39) | 0.94 |
| 5 | 3/31 (10) | 2/8 (25) | 1/23 (4) | 0.16 |
| Week 13 | ||||
| GBS disability score (%) | ||||
| 0–2 | 21/30 (70) | 4/8 (50) | 16/21 (76) | 0.20 |
| 3–4 | 6/30 (20) | 2/8 (25) | 4/21 (19) | 0.72 |
| 5 | 0 (0) | 0 (0) | 0 (0) | – |
| 6 | 3/30 (10) | 2/8 (25) | 1/21 (5) | 0.18 |
Results are given as median (25th–75th percentile) or as counts (percentage). MRC sum = sum of Medical Research Council scores for muscle groups for shoulder abduction, elbow flexion, wrist extension, hip flexion, knee extension and ankle dorsiflexion of both limbs.
*
Significant values (P < 0.05).
a
Classification by the ECDC case definitions. Unclassifiable patients (n = 2) are not shown.