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. 2021 Sep 20;144(11):3451–3460. doi: 10.1093/brain/awab326

Figure 1.

Figure 1

Repeat length, age at diagnosis and gender. Cumulative probability plots were used to compare repeat length and age at diagnosis (A), as well as repeat length and age at diagnosis with respect to gender (B). (A) A median age of diagnosis of 14 (95% CI: 11, 17) for all individuals with 1–3 repeats; 30 years (95% CI: 27, 34) for all individuals with 4–7 repeats; and 40 years (95% CI: 35, 46) for all individuals with 8–10 repeats. When separated by gender (B), there does appear to be a separation in the age at which males and females with 4–7 repeats were diagnosed. Males had a median age of diagnosis of 25 (95% CI: 24, 30) whereas females had a median age of diagnosis of 35 (95% CI: 30, 37). There is no difference in the median age at diagnosis for males and females with 1–3 or 8–10 repeats. Females in the 1–3 repeat category were diagnosed at a median age of 11 (95% CI: 10, 17) whereas males were diagnosed at a median age of 16 (95% CI: 13, 33). Females in the 8–10 repeat category were diagnosed at a median age of 42 (95% CI: 33, 55) whereas males were diagnosed at a median age of 38.5 (95% CI: 32, 47).