Table 1.
Participant characteristics
| Healthy volunteers |
TBI patients |
||
|---|---|---|---|
| 18F-FDG (n = 9) | 15O (n = 20) | Total (n = 26) | |
| Age, years | 56 (53–57) | 43 (31–47) | 40 (26–52) |
| Gender, female/male | 6/3 | 5/15 | 4/22 |
| GCS post-resuscitation | – | – | 6 (3–9) |
| Injury mechanism | |||
| Fall | – | – | 10 |
| Road traffic collision | – | – | 16 |
| Marshall classification | |||
| Diffuse injury I | – | – | 0 |
| Diffuse injury II | – | – | 5 |
| Diffuse injury III | – | – | 0 |
| Diffuse injury IV | – | – | 0 |
| Evacuated mass lesion V | – | – | 13 |
| Non-evacuated mass lesion VI | – | – | 8 |
| Primary lesion | |||
| Subdural haematoma | – | – | 5 |
| Contusion | – | – | 18 |
| DAI, IVH and tSAH | – | – | 3 |
| Craniectomy | – | – | 12 |
| Barbiturate coma | – | – | 2 |
| Hypothermia | – | – | 1 |
| Blood glucose, mmol/l | 4.6 (4.4–5.4) | – | 5.8 (5.3–6.7) |
| Outcome (GOS) | – | – | 3 (3–4)a |
Characteristics of the TBI patients who underwent combined 18F-FDG and 15O PET, and the healthy volunteers who underwent separate 18F-FDG and 15O PET sessions. Data shown are median (IQR). DAI = diffuse axonal injury; GCS = Glasgow Coma Scale; IVH = intraventricular haemorrhage; tSAH = traumatic subarachnoid haemorrhage. Blood glucose is the mean value of this variable over the course of each PET study.
a
Two missing data-points for GOS.