TABLE 3.
Association of endothelial function, arterial elasticity, and arterial stiffness with cardiorespiratory fitness, fat mass, lean mass, and adiponectin.
| n = 5566Variable | CRF (W) | CRFper BM0.21 (W·kg BM−0.21) | CRFper LM0.54 (W·kg LM−0.54) | Adiponectina (μg·mL−1) | Total Fat Massa (kg) | Trunk Fat Massa (kg) | Lean Mass (kg) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β (95% CI) | P | β (95% CI) | P | β (95% CI) | P | β (95% CI) | P | β (95% CI) | P | β (95% CI) | P | β (95% CI) | P | |
| Model 1 | ||||||||||||||
| Flow-mediated dilation (%) | −0.099 (−0.161 to −0.037) | 0.002 | −0.038 (−0.066 to −0.009) | 0.010 | 0.003 (−0.008 to 0.013) | 0.615 | <0.001 (−0.004 to 0.004) | 0.979 | 0.003 (−0.001 to 0.008) | 0.187 | 0.005 (<0.001 to 0.010) | 0.059 | −0.081 (−0.106 to −0.056) | <0.0001 |
| Distensibility coefficienta (% per mm Hg) | 0.570 (0.109 to 1.031) | 0.015 | 0.214 (−0.001 to 0.429) | 0.051 | 0.058 (−0.019 to 0.135) | 0.137 | −0.006 (−0.036 to 0.024) | 0.695 | 0.018 (−0.015 to 0.051) | 0.283 | 0.025 (−0.014 to 0.063) | 0.211 | 0.178 (−0.007 to 0.362) | 0.059 |
| Carotid–radial pulse wave velocity (m·s−1) | −0.362 (−0.534 to −0.189) | <0.0001 | −0.017 (−0.097 to 0.062) | 0.668 | −0.016 (−0.045 to 0.013) | 0.267 | 0.010 (<0.001 to 0.020) | 0.044 | −0.081 (−0.093 to −0.069) | <0.0001 | −0.095 (−0.109 to −0.080) | <0.0001 | −0.192 (−0.262 to −0.123) | <0.0001 |
| Model 2 | ||||||||||||||
| Flow-mediated dilation (%) | 0.019 (−0.043 to 0.081) | 0.549 | 0.003 (−0.027 to 0.032) | 0.862 | −0.003 (−0.014 to 0.008) | 0.558 | −0.004 (−0.008 to <0.0001) | 0.056 | 0.012 (0.008 to 0.016) | <0.0001 | 0.016 (0.011 to 0.020) | <0.0001 | 0.027 (0.007 to 0.047) | 0.009 |
| Distensibility coefficienta (% per mm Hg) | 0.594 (0.156 to 1.031) | 0.008 | 0.242 (0.033 to 0.451) | 0.023 | 0.050 (−0.025 to 0.125) | 0.193 | −0.008 (−0.039 to 0.022) | 0.585 | 0.004 (0.002 to 0.006) | <0.0001 | 0.005 (0.002 to 0.007) | <0.0001 | 0.229 (0.088 to 0.369) | 0.001 |
| Carotid–radial pulse wave velocity (m·s−1) | −0.148 (−0.316 to 0.020) | 0.083 | −0.076 (−0.155 to 0.004) | 0.063 | −0.030 (−0.060 to −0.001) | 0.043 | 0.005 (−0.005 to 0.015) | 0.350 | −0.050 (−0.060 to −0.039) | <0.0001 | −0.057 (−0.070 to −0.045) | <0.0001 | 0.013 (−0.040 to 0.067) | 0.628 |
The regression coefficient (β) quantifies the association between dependent and independent variables. A two-sided P value <0.05 was considered statistically significant and is bolded.
Model 1: unadjusted associations of arterial function and structure with cardiorespiratory fitness, fat mass, lean mass, and adiponectin. Model 2: associations were adjusted for age, sex, puberty, systolic blood pressure, mother’s socioeconomic status, total fat mass or cardiorespiratory fitness/lean mass, LDL, diameter of the brachial artery, and time between measures of exposure and outcome variable.
aLogarithm transformation of skewed variables was used in analyses.
BM, body mass; CI, confidence interval; CRF, cardiorespiratory fitness; LM, lean mass; W, watt.