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. 2021 Dec 3;11:772962. doi: 10.3389/fcimb.2021.772962

Figure 2.

Figure 2

Analyses of bacterial alpha diversities of the microbiome at three anatomical sites from EAE mice with or without CMG administration. Using QIIME 2, we compared the number of genera, evenness, and combination of them by the Faith’s phylogenetic diversity (A–C), Pielou’s evenness (D–F), and Shannon (G–I) indexes, respectively, between the three CMG administration (Induction, blue; Latent, red; and Whole, green) and control groups (Control, black). We found no difference in the Faith’s (A–C) or Shannon index (G–I) among the CMG-treated and Control groups, although the Pielou’s index was significantly different between the Control versus Whole, the Control versus Induction groups in feces (D), and the Control versus Latent groups in ileal contents (E), all of which had decreased diversity in the CMG-treated groups (*P < 0.05, Kruskal-Wallis test) (D, E).