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. 2021 Dec 3;11:772962. doi: 10.3389/fcimb.2021.772962

Table 5.

Numbers of pathways changed in the CMG-treated groups by PICRUSt.

Groups Induction Latent Whole
Feces Increased 5 a, b 0 36 a, b, d
Decreased 0 0 2
Ileal contents Increased 0 59 a, c 26 a, c, d
Decreased 2 0 4
Ileal mucosa Increased 0 0 0
Decreased 0 0 23

Significantly changed pathways compared with the Control group (P < 0.05).

a

Pathway commonly increased in feces of the Induction and Whole groups, and ileal contents of the Latent and Whole groups (n = 1).

1. Cell division.

b

Pathways commonly increased in feces of the Induction and Whole groups (n = 5).

1. Cell division; 2. Glycosphingolipid biosynthesis - ganglio series; 3. 1,1,1-Trichloro-2,2-bis(4-chlorophenyl) ethane (DDT) degradation; 4. Toluene degradation; and 5. Glycan biosynthesis and metabolism.

c

Pathways commonly increased in ileal contents of the Latent and Whole groups (n = 10).

1. Cell division; 2. Peroxisome; 3. Primary immunodeficiency; 4. Infectious diseases, pertussis; 5. Oxidative phosphorylation; 6. Biotin metabolism; 7. Folate biosynthesis; 8. Ubiquinone and other terpenoid-quinone biosynthesis; 9. β-Alanine metabolism; and 10. Membrane and intracellular structural molecules.

d

Pathways commonly increased in feces and ileal contents of the Whole group (n = 15).

1. Cell division; 2. Peroxisome; 3. Infectious diseases, pertussis; 4. Citrate cycle (TCA cycle); 5. Oxidative phosphorylation; 6. Lipopolysaccharide biosynthesis; 7. Lipopolysaccharide biosynthesis proteins; 8. Biotin metabolism; 9. Ubiquinone and other terpenoid-quinone biosynthesis; 10. β-Alanine metabolism; 11. 1,1,1-Trichloro-2,2-bis(4-chlorophenyl) ethane (DDT) degradation; 12. Toluene degradation; 13. Adipocytokine signaling pathway; 14. Membrane and intracellular structural molecules; and 15. Glycan biosynthesis and metabolism.