Table 1.

Univariate and Multivariate cox regression analysis-TCGA cohort.

Variables	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Risk score	2.113 (1.388-3.215)	<0.001	2.104 (1.343-3.295)	0.001
Stage (III+IV/I+II)	2.390 (1.165-4.903)	0.017	1.632 (0.771-3.453)	0.200
Grade (2 + 3/1)	1.616 (0.557-4.684)	0.377
pT (3 + 4/1+2)	1.279 (0.615-2.662)	0.510
pN (1 + 2+3/0)	1.988 (0.962-4.108)	0.063
pM (1/0)	2.265 (0.671-7.644)	0.188
Gender (Male/Female)	5.266 (1.221-22.71)	0.026	3.277 (0.745-14.405)	0.116
Age (≥65/65)	1.838 (0.822-4.112)	0.138
Smoke (yes/no)	1.564 (0.671-3.647)	0.301