Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Therapies targeting PI3K/Akt signaling
| Agent | Targets | Inhibitors |
|---|---|---|
| Apoptosis | p53 | BKM120 |
| CAL-101 | ||
| GDC0068 | ||
| p-S6 | BYL719 | |
| GDC-0068 | ||
| Rapamycin | ||
| p38 | GSK2141795 | |
| Proliferation | p53 | Bez235 |
| Temsirolimus | ||
| p-S6 | XL765 | |
| XL147 | ||
| GSK2121183 | ||
| LY2780301 | ||
| Rapamycin | ||
| Deforolimus | ||
| CDK1 | Everolimus | |
| TGF-β1 | Bez235 | |
| Autophagy | LC3B | MK2206 |
| p-S6 | AZD5363 |
