Table 2.
Clinical outcomes by sexa.
| Patients, No. (%) | |||
| Outcome | All (N = 4407) | Men (n = 2793) | Women (n = 1614) |
| Died within 28 d | 1625 (36.9) | 1072 (38.4) | 553 (34.3) |
| Causes of deathb | |||
| Respiratory failure | 1605 (98.8) | 1052 (98.1) | 553 (100) |
| Heart failure | 181 (11.1) | 122 (11.5) | 59 (10.7) |
| Septic shock | 710 (43.7) | 477 (44.5) | 233 (42.1) |
| Kidney failure | 619 (38.1) | 436 (40.7) | 183 (33.1) |
| Liver failure | 83 (5.1) | 51 (4.8) | 32 (5.8) |
| Other | 252 (15.5) | 178 (16.6) | 74 (13.4) |
| Severe acute kidney injuryc | 829 (19.5) | 590 (21.8) | 239 (15.5) |
| Length of kidney replacement therapy d, median (IQR) | 6 (3–10) | 6 (3–10) | 7 (3–11) |
| Respiratory failure | 3489 (79.2) | 2255 (80.7) | 1234 (76.5) |
| Length of mechanical ventilation d, median (IQR) | 11 (6–14) | 11 (6–14) | 11 (6–14) |
IQR = interquartile range.
a
Data are presented as number of patients (percentage).
b
Defined as per medical record review. Patients could have had more than one cause of death.
c
Patients with end-stage kidney disease (n = 156) were excluded from the denominator for analyses of acute kidney injury.