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. 2021 Dec 3;8:784876. doi: 10.3389/fmolb.2021.784876

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Copyright © 2021 Parente, Rossi, Sparaneo, Fabrizio, Centonza, Taurchini, Mazza, Cassano, Miscio, Centra, Ferretti, Di Micco, Graziano and Muscarella.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Case 1, pulmonary lesion. Intraparenchymal neoplasm consisting of glandular component corresponding to lepidic-papillary pulmonary adenocarcinoma, on the left, and of adhered trabecular proliferation of monomorphic epithelioid cells corresponding to atypical carcinoid, on the right; hematoxylin/eosin, 0.5x (A) and 5.5x (C). Immunostaining showing diffuse and strong immunoreactivity for Synaptophysin only in the carcinoid component (on the right, 5.5x; B, D) and immunoreactivity for TTF-1 in both component (5.5x, D).