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. 2021 Dec 2;12:783722. doi: 10.3389/fmicb.2021.783722

TABLE 4.

Treatments and survival rates in the in vivo rescue experiments in the mouse lung infection model.

Group Bacterium dilution Bacterium cfu/mouse FSF mg/mouse Phage MOI Phage pfu/mouse Survival 10 days
1 A. PBS control
- - - - - 100%
2 B. PIAS control
- - - - 25,000,000 100%
3 C. fosfomycin control
- - 1.0 - - 100%
4 D. Bacterium PA16 dilution controls
5x 5,000,000 - - - 0%
15x 1,600,000 - - - 75%
5 E. Bacterium PA16 + Phage PIASPA16g
5x 5,000,000 - 0.2 1,000,000 0%
5x 5,000,000 - 1.0 5,000,000 0%
5x 5,000,000 - 5.0 25,000,000 25%
6 F. Bacterium PA16 + fosfomycin
5x 5,000,000 1.0 - - 0%
7 G. Bacterium PA16 + fosfomycin + Phage PIASPA16g
5x 5,000,000 1.0 0,2 1,000,000 25%
5x 5,000,000 1.0 1.0 5,000,000 25%
5x 5,000,000 1.0 5.0 25,000,000 75%