TABLE 3.
Correlation analysis between ALDOA and immune infiltration markers in TIMER.
| Description | Gene markers | Lung adenocarcinoma | |||
|---|---|---|---|---|---|
| None | Purity | ||||
| Cor | p | Cor | p | ||
| B cell | CD19 | −0.157 | ** | 0.039 | 3.92e-01 |
| CD79A | −0.106 | 1.59e-02 | −0.104 | 2.04e-02 | |
| CD8+ T cell | CD8A | −0.133 | * | −0.133 | * |
| CD8B | −0.150 | ** | −0.147 | * | |
| T cell (general) | CD3D | −0.130 | * | −0.125 | * |
| CD3E | −0.169 | ** | −0.176 | *** | |
| CD2 | −0.162 | ** | −0.166 | ** | |
| M1 Macrophage | INOS (NOS2) | −0.012 | 7.79e-01 | −0.010 | 8.24e-01 |
| IRF5 | −0.023 | 6.08e-01 | 0.037 | 4.15e-01 | |
| COX2 (PTGS2) | 0.005 | 9.03e-01 | −0.001 | 9.74e-01 | |
| M2 Macrophage | CD163 | −0.030 | 5.03e-01 | −0.004 | 9.22e-01 |
| VSIG4 | −0.042 | 3.36e-01 | −0.028 | 5.38e-01 | |
| MS4A4A | −0.154 | ** | 0.039 | 3.92e-01 | |
| Neutrophils | CD66b (CEACAM8) | −0.180 | *** | −0.183 | ** |
| CD11b (ITGAM) | 0.023 | 6.06e-01 | 0.123 | 3.00e-01 | |
| CCR7 | −0.199 | *** | −0.203 | *** | |
| Dendritic cell | HLA-DPB1 | −0.164 | ** | −0.156 | ** |
| HLA-DQB1 | −0.101 | 2.15e-02 | −0.085 | 5.84e-02 | |
| HLA-DRA | −0.157 | ** | −-0.144 | * | |
| HLA-DPA1 | −0.122 | * | −0.111 | 1.34e-02 | |
| BDCA-1 (CD1C) | −0.249 | *** | −0.240 | *** | |
| BDCA-4 (NRP1) | 0.033 | 4.59e-01 | 0.033 | 4.59e-01 | |
| CD11c (ITGAX) | −0.002 | 9.69e-01 | 0.015 | 7.33e-01 | |
Cor, correlation of Spearman’s R value; None, correlation with no adjustment; Purity, correlation with adjusted by purity.
p < 0.01; p < 0.001; p < 0.0001.