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Changes in Toll-like receptor 4 (TLR4) signaling in canonical myeloid differentiation primary response 88 (MyD88)-mediated signaling pathways. Presented as fold change relative to healthy controls, which were normalized to a baseline of zero. NFκB = nuclear factor kappa B; IL-6 = interleukin 6; IL-6R = interleukin 6 receptor; TNFa = tumor necrosis factor alpha; IL-1b = interleukin 1 beta; *p<0.05 vs. healthy controls; #p<0.05 elective hip replacement vs. trauma patients
