Table 2.
Models | Sub-distribution HR (95% CI)* | Cause-specific HR (95% CI)* |
---|---|---|
Model 1 | 1.36 (1.27-1.46) | 1.37 (1.28-1.46) |
Model 2 | 1.24 (1.14-1.34) | 1.25 (1.15-1.34) |
Model 3 | 1.18 (1.09-1.28) | 1.19 (1.09-1.29) |
Model 4 | 1.19 (1.09-1.28) | 1.20 (1.10-1.29) |
CI – confidence interval; HR – hazard ratio
Model 1 - calendar year and graft failure
Model 2 – model 1 + age at time of transplant, sex, race, BMI, cause of ESRD and modality duration and dialysis vintage
Model 3 – model 2 + comorbidities, health care utilization metrics and prior solid organ transplant status
Model 4 – model 3 + transplant characteristics
Graft failure was treated as a time-varying covariate. All models stratified by incidence year categories (2005-2006, 2007-2008, 2009-2010, and 2011-2012)
Sub-distribution hazard ratio treats death as a competing event; cause-specific hazard ratio treats death as a censoring event.