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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: J Biomed Mater Res A. 2021 Jul 29;110(2):245–256. doi: 10.1002/jbm.a.37280

Figure 4. Susceptibility to calcification of GF-BP, ePC-UPy, UBM-ECM, and PP.

Figure 4.

(A) Representative images of calcification within GF-BP and ePC-UPy as indicated by radiographic imaging. Red dotted lines define the edge of the material, yellow arrows indicate focal calcification. (B) Mineralization of GF-BP observed histologically by von Kossa (black arrow) and lack of mineralization observed in ePC-UPy, UBM-ECM, and PP at day 21. These comparisons indicate that the susceptibility to calcification often observed for bioprosthetic material, exemplified here for GF-BP, is absent with ePC-UPy, UBM-ECM and PP. (B) von Kossa stain, scale bars 400μm.